Use of selected cyclosporins for the treatment of hepatitis...

Details Use of selected cyclosporins for the treatment of hepatitis... Use of selected cyclosporins for the treatment of hepatitis...

2006-04-12

2008-10-21

Tate, Christopher R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

Reexamination Certificate

active

07439227

ABSTRACT:
This invention relates to the use in the treatment of HCV infection, either as single active agents or in combination with another active agent, of a cyclosporin having increased cyclophilin binding activity and essentially lacking immunosuppressive activity.

REFERENCES:
patent: 6927208 (2005-08-01), Wenger et al.
patent: WO 98/28328 (1998-07-01), None
patent: WO 98/28329 (1998-07-01), None
patent: WO 00/01715 (2000-01-01), None
patent: WO 2005/021028 (2005-03-01), None
Watashi et al., Hepatology, 2003, vol. 38, pp. 1282-1288.
Nakagawa et al., Specific inhibition of hepatitis C virus replication by cyclosporin A. Biochem. Biophys. Res. Commun. 313: 42-7 (2004).
Watashi, K. et al., Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes. Hepatology 38: 1282-1288 (2003).
Inoue K. et al., Interferon combined with cyclosporine treatment as an effective countermeasure . . . Transplantation Proceedings, Orlando, FL, vol. 37, pp. 1233-1234, 2005.
Inoue K. et al., Combined interferon alpha2b and cyclosporin A . . . J. Gastroenterol. 38: 567-72 (2003).
Huebler F. et al., Synthetic routes to NEt-Xaa4-cyclosporin A derivatives as potential anti-HIV I drugs. Tetrahedron Lett. (Elsevier, Amsterdam) 41: 7193-6 (2000).
Xia Wei-Liang et al., Inhibitory effect of cyclosporine A on hepatitis B . . . Hepatobiliary & Pancreatic Diseases International 4: 18-22 (2005) (ISSN 1499-3872).
Hansson M. et al., The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 . . . J. Bioenergetics & Biomembranes (Plenum, N.Y.) 36: 407-13 (2004).

Affiliated with

Also associated with

Rating

Use of selected cyclosporins for the treatment of hepatitis... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of selected cyclosporins for the treatment of hepatitis..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of selected cyclosporins for the treatment of hepatitis... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3991507