Use of RIP in treating staphylococcus aureus infections

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S184100, C424S190100, C424S236100, C424S237100, C424S239100, C424S241100, C424S243100, C424S246100, C424S247100, C424S257100, C424S422000, C424S423000, C424S430000, C514S008100, C514S002600

Reexamination Certificate

active

07824691

ABSTRACT:
The present composition combines an RNAIII-inhibiting peptide (RIP) with an antimicrobial peptide, such as a cathelicidin, that is capable of binding and neutralizing lipidic and polyanionic components of bacterial cell envelope. In another embodiment, the RIP is combined with an antibiotic, with or without an antimicrobial peptide. The present composition is advantageously used in a method of treatment of bacterial sepsis.

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