Use of (R)-peniciclovir triphosphate for the manufacture of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S263370, C514S081000

Reexamination Certificate

active

07045525

ABSTRACT:
A method of treatment of: i) HIV-1 infections in mammals, including humans; or ii) HBV infections in mammals, including humans; which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A) or a pharmaceutically acceptable salt thereof; and compounds for use in the method.

REFERENCES:
patent: 0 388 049 (1990-09-01), None
patent: WO 92/00742 (1992-01-01), None
Mok et al.,Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy, Abstracts No. H66, 35(0), p. 191 (1995).
Schinazi et al.,Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy, Abstract No. H104, 35(0), p. 198 (1995).
Earnshaw et al.,Antimicrob. Agents Chemother., 36(12), pp. 2727-2757 (1992).
Vere Hodge et al.,Antiviral Chemistry&Chemotherapy, 4(Supplement 1), pp. 13-24 (1993).
Abstacts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy, Session 43, p. 182 and p. 191 (Sep. 17-20, 1995).
Program and Abstracts of the Eighth International Conference on Antiviral Research, Poster Session II, p. A304 (Apr. 23-28, 1995).

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