Use of purinergic receptor agonists as antineoplastic agents

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 47, 514 48, A61K 3170, A61K 908

Patent

active

054158737

ABSTRACT:
The instant invention is directed to the use of a pharmaceutical composition containing an effective amount of adenosine or an adenosine analog or derivative as an agent useful in the treatment of hormone-independent cancers, such as prostate cancer. The invention is also directed to diagnostic uses of these compounds to determine effective treatment regimes for specific tumors, a process for screening for new, therapeutically useful analogs of these compounds, and the use of these compounds in facilitating the extraction of intracellular components.

REFERENCES:
patent: 4690935 (1987-09-01), Taylor et al.
patent: 4950680 (1990-08-01), Taylor et al.
Roth, All about Cancer 1987, p. 14.
Rapaport Eur. J. Cancer Clin. Oncol. 24, 1491-7 (1988).
Ogreid. Cancer Res. 47, p. 2576 (1987).
Koschel Eur. J. Biochem 108, 163 (1980).
O'Connor et al, Trends in Pharmaceutical Sciences, 12:137-141 (1991).
Gordon, Biochem. J., 233:309-319 (1986).
Webster's II New Riverside University Dictionary, p. 104 (1984).
Fraumeni, Jr. et al., Principles and Practice of Oncology, 3rd Edition, 1989 Kerr et al., Virchows Arch. Abt. B. Zellpath. 13.87 102 (1973).
Kyprianou et al, The Prostate 13:103-117 (1988).
Smith et al, Nature, vol. 337, pp. 181-184.
Trepel et al., Biochem. J. (1988) 255, 403, 410 (Printed in Great Britain).
Ucker et al., Nature, vol. 327, pp. 62-64, 1987.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of purinergic receptor agonists as antineoplastic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of purinergic receptor agonists as antineoplastic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of purinergic receptor agonists as antineoplastic agents will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-636432

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.