Use of purinergic receptor agonists as antineoplastic agents

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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514 47, 514 48, 514279, A61K 3170, A61K 908

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active

056415001

ABSTRACT:
The instant invention is directed to the use of a pharmaceutical composition containing an effective amount of adenosine or an adenosine analog or derivative as an agent useful in the treatment of hormone-independent cancers, such as prostate cancer. The invention is also directed to diagnostic uses of these compounds to determine effective treatment regimes for specific tumors, a process for screening for new, therapeutically useful analogs of these compounds, and the use of these compounds in facilitating the extraction of intracellular components.

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