Use of pseudopterosins for promoting wound healing

Details Use of pseudopterosins for promoting wound healing Use of pseudopterosins for promoting wound healing

1995-06-07

1997-01-28

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 181, A61K 3170

Patent

active

055978088

ABSTRACT:
Methods of promoting wound healing and the growth and proliferation of keratinocytes, fibroblasts and endothelial cells are disclosed. These methods comprise contacting a wound with an effective wound healing amount of a composition comprising a pseudopterosin or pseudopterosin derivative.

REFERENCES:
patent: 4745104 (1988-05-01), Jacobs et al.
patent: 4849410 (1989-07-01), Jacobs et al.
Look, S. A., et al., "The Pseudopterosins: Anti-inflammatory and Analgesic Natural Products from the Sea Whip Pseudopterogorgia Elisabethae," Proc. Natl. Acad. Sci. USA, 83:6238-6240 (Sep. 1986).
Look S. A. and Fenical, W., "The Seco-Pseudopterosins, New Anti-inflammatory Diterpene-Glycosides from a Caribbean Gorgonian Octocoral of the Genus Pseudopterogorgia," Tetrahedron, 43(15):3363-3370 (1987).
Roussis, V., et al., "New Antiinflammatory Pseudopterosins from the Marine Octocoral Pseudopterogorgia Elisabethae," J. Org. Chem., 55:4916-4922 (1990).
Look , S. A. et al., "The Pseudopterosins: A New Class of Antiinflammatory and Analgesic Diterpene Pentosides from the Marine Sea Whip Pseudopterogorgia Elisabethae (Octocorallia)," J. Org. Chem., 51(26):5140-5145 (1986).

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