Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent
Patent
1996-06-07
1999-11-02
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Ultrasound contrast agent
A61B 813
Patent
active
059765011
ABSTRACT:
Conventional ultrasonic imaging methods are described which involve the use of aqueous suspension of microspheres. These microspheres are further characterized as consisting of gas cores encapsulated by a protein shell which are formed in the presence of perfluoroalkane vapors. The presence of the vapor during formation changes the shell characteristics and thus protects the gas from being solubilized in the surrounding aqueous environment. In addition, the presence of the perfluoroalkane vapor during formation may also provide improved echogenic properties for vascular imaging applications.
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Hollinden Gary E.
Molecular Biosystems, Inc.
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