Use of porphyrin-complex or expanded porphyrin-complex compounds

Details Use of porphyrin-complex or expanded porphyrin-complex compounds Use of porphyrin-complex or expanded porphyrin-complex compounds

1997-03-17

2000-01-11

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 9362, 424 961, A61K 5104, A61K 4900, A61B 5055

Patent

active

060132418

ABSTRACT:
The invention relates to the use of porphyrin-complex or expanded porphyrin-complex compounds for the manufacture of a diagnosticum for the localization of an infarction and of a necrosis, wherein the infarction or necrosis may comprise an infarction of heart, kidney, intestine, lung, and/or brain, and wherein the porphyrin-complex compound may be Gd-MP and/or Mn-TPP.

REFERENCES:
patent: 5284647 (1994-02-01), Niedballa et al.
The New International Webster's Comprehensive Dictionary of the English Language, 1996 Edition, pp. 1204-1205.
Ince et al., "Heterogeneity of the hypoxic state in rat heart is determined at capillary level." American Journal of Physiology: Heart and Circulatory Physiology, vol. 33, No. 2, pp. 295-301 (1993).
Bockhorst et al., "Localization of Experimental Brain Tumors in MRI by Gadolinium Porphyrin," Acta Neurochir, 60: 347-349 (1994).
Ross et al., "Myoglobin as an Oxygen Indicator for Measuring the Oxygen Binding Characteristics of a Modified Myoglobin Derivative Containing Covalently Bound Mesoheme," Pennsylvania State University (1977).

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