Use of polycarboxylic acid polymers to treat vaginal infections

Details Use of polycarboxylic acid polymers to treat vaginal infections Use of polycarboxylic acid polymers to treat vaginal infections

1997-10-16

2000-01-25

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

424 7807, 424430, 514967, A61K 3178

Patent

active

060175214

ABSTRACT:
The present invention relates to the use of a bioadhesive aqueous composition to control the pH of the vagina to alleviate microorganism growth and feminine odor such as presented by bacterial vaginosis. The composition contemplated herein comprises water and an acidic polymer, specifically one wherein 80% of the monomers contain at least one carboxyl group [--COOH] and wherein the polymer is cross-linked so as to be water-swellable, but water-insoluble. The composition of the present invention is additionally a bioadhesive providing for a long-lasting benefit and control of vaginal pH.

REFERENCES:
patent: 2923692 (1960-02-01), Ackerman et al.
patent: 4032269 (1977-06-01), Osberghaus
patent: 4296096 (1981-10-01), Pierce
patent: 4548990 (1985-10-01), Mueller
patent: 4552755 (1985-11-01), Randen
patent: 4597965 (1986-07-01), Holly
patent: 4615697 (1986-10-01), Robinson
patent: 4698359 (1987-10-01), Niederer et al.
patent: 4863725 (1989-09-01), Deckner et al.
patent: 4900554 (1990-02-01), Yanagabashi
patent: 4933182 (1990-06-01), Higashi et al.
patent: 5143731 (1992-09-01), Viegas et al.
6001 Chemical Abstracts 99 (1983) Oct. No. 14, Columbus, Ohio, USA.
Breen, J., ed. The Gynecologist and the Older Patient, pp. 304-305 (1988).
Kaufman et al., Benign Diseases of the Vulva and the Vagina, 3rd ed., pp. 401-418 (1989).
Barbone et al.,"A Follow-up Study of Methods of Contraception, Sexual Activity and Rates of Trichomoniasis, Candidiasis and Bacterial Vaginosis," Am. J. Obstet. Gynecol., vol. 163, No. 2, p. 515 (Aug. 1990).
Andersen et al., "Treatment of Bacterial Vaginosis with an Acid Cream: A Comparison between the Effect of Lactate Gel and Metronidazole", Gynecol. Obstet. Invest., 21:19-25 (1986).
Zinny, M. and Lee, S., "Double-Blind Study of the Comparative Effects of Two Gels on Vaginal pH in Postmenopausal Women", Today's Therapeutic Trends, 8(4):65-72 (1992).
Bachmann et al., "Vaginal Dryness in Menopausal Wioemn: Clinical Characteristiccs and Nonhormonal Treatment", Clinical Practice in Sexuality, vol. 7, No. 9, 1-8 (1991).

Affiliated with

Also associated with

Rating

Use of polycarboxylic acid polymers to treat vaginal infections does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of polycarboxylic acid polymers to treat vaginal infections, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of polycarboxylic acid polymers to treat vaginal infections will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2313771