Use of polyacrylates to reduce proteolytic activity in the human

Details Use of polyacrylates to reduce proteolytic activity in the human Use of polyacrylates to reduce proteolytic activity in the human

1989-07-07

1991-09-24

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3178

Patent

active

050512536

ABSTRACT:
A method for the treatment of inflammatory bowel disease which comprises administering to a patient an effective oral or rectal amount of a polyacrylate. There are also described compositions for use in the method.

REFERENCES:
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patent: 3930005 (1975-12-01), Wojnor et al.
patent: 4273761 (1981-06-01), Matsuda et al.
patent: 4705683 (1987-11-01), Dettmar
Marshall, "The Isolation and Characterization of the High-Molecular-Weight Glycoprotein from Pig Colonic Mucus", Biochem J. (1978), 173, 569-578.
Ishii, "Effects of Sodium Polyacrylate (PANa) on Peptic Ulcers in Rats", Oyo Yakuri (1982) 23 (1) 55-62.
Hill, "The Possible Role of Bacteria in Inflammatory Bowel Disease", Current Concepts in Gastroenterology, Winter 1985, pp. 8-13.

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