Use of platelet polymorphism P1A2 to diagnose risk of thrombotic

Details Use of platelet polymorphism P1A2 to diagnose risk of thrombotic Use of platelet polymorphism P1A2 to diagnose risk of thrombotic

1996-04-01

1999-09-21

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 243, 935 8, 935 77, 935 78, 435 912, C12Q 168, C07H 2104, C12P 1934

Patent

active

059552662

ABSTRACT:
A method for diagnosing a subject having or at risk of having a thrombotic disease syndrome by analysis of a platelet polymorphism is provided. The association between a polymorphism of the Pl.sup.A2 allele of the GPIIIa gene and unstable thrombotic syndromes provides the basis for methods and kits for diagnosing subjects.

REFERENCES:
patent: 5091302 (1992-02-01), Newman et al.
Dorland's Illustrated Medical Dictionary, W.B. Saunders Co., Philadelphia (1994) pp. 1706-1708, 1994.
Stratagene Catalog (1988) p. 39, 1988.
McFarland et. al. Blood 78: 2276-2282 (Nov. 1991).
Wang et. al. The Journal of Clinical Investigation 90:2038-2043 (Nov. 1992).
Weiss et al Circulation 92: I-30 abstract 0138 (Oct. 1995).
Jin et. al. Blood 82:2281-2288. (Oct. 1993).
E. J. Weiss, et al., A monoclonal antibody (SZ21) specific for platelet GPIIa distinguishes P1.sup.A1 from P1.sup.A2, Tissue Antigens 1995: 46: pp. 374-381.
Paul F. Bray et al., Rapid Genotyping of the Five Major Platelet Alloantigens by Reverse Dot-Blot Hybridization, Blood, vol. 84, No. 12, Dec. 12, 1994, pp. 4361-4367.

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