Use of platelet derived growth factor to enhance wound healing

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 2, 514912, A61K 3700, A61K 3718

Patent

active

059554363

ABSTRACT:
Disclosed is the use of platelet derived growth factor for the enhancement of wound healing wherein the growth factor is either singularly or multiply dosed on a single day, rather than multiply dosed over a number of days. Also disclosed are pharmaceutical compositions comprising platelet derived growth factor.

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Lynch, S. E. et al., "Role of platelet-derived growth factor in wound healing: Synergistic effects with other growth factors," PNAS, 84:7696-7700 (1987).
Ksander, G. A., "Exogenous Growth Factors in Dermal Wound Healing," Ann. Rep. Med. Chem., 24:223-232 (1989).
Nakada, S. et al. "Effect of PDGF, IGF and EGF on Corneal Epithelial Wound Healing and Reinnervation," Invest. Ophthal. Vis. Sci., 31(4):54 (1990).
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Harvey, A. K. et al., "Chemotaxis of Rat Retinal Glia to Growth Factors Found in Repairing Wounds," Invest. Ophthalmol. Vis. Sci., 28:1092-1099 (1987).
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