Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-02-19
1983-12-13
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544360, 544372, 544365, C07D40300, C07D40100, A61K 31495
Patent
active
044204817
ABSTRACT:
The present invention relates to a novel piperazine compound represented by the following general formula (I): ##STR1## wherein R stands for an alkyl or phenyl group, and n is a number of 4 or 5.
These compounds are valuable as an immunopotentiators, such as for the treatment of chronic rheumatoid arthritis and other diseases accompanied by reduction or abnormal change of immune function.
REFERENCES:
patent: 3133067 (1964-05-01), Archer
patent: 3250771 (1966-05-01), Leonard et al.
patent: 3509171 (1970-04-01), Welstead et al.
Baltzly et al., Journal of American Chem. Soc., vol. 66, pp. 263-266, (1944), "The Preparation of N-Mono-Substituted & Unsymmetrically Disubstituted Piperazines.
Miyahara Shiyoichiro
Okazaki Yutaka
Tokuda Hiroshi
Yamada Yoshitsugu
Daus Donald G.
Gibson S. A.
Mitsuitoatsu Chemicals Inc.
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