Use of Phthalidyliden esters of carnitine and alkanoyl carnitine

Details Use of Phthalidyliden esters of carnitine and alkanoyl carnitine Use of Phthalidyliden esters of carnitine and alkanoyl carnitine

1995-09-19

1998-09-29

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514468, 514921, A61K 3134

Patent

active

058146610

ABSTRACT:
A therapeutical method for treating endotoxic shock which comprises administering to a patient in need thereof a (3-phthalidyliden) alkyl ester of carnitine or alkanoyl carnitine, is disclosed.

REFERENCES:
patent: 4582824 (1986-04-01), Nishikawa et al.
Vito Ruggiero et al. "LPS-Induced Serum TNF Production and Lethality in Mice: Effect of L-Carnitine and Some Acyl-Derivatives". Mediators of Inflammation, vol. 2(Supplement), pp. S43-S50. 1993.
CAPLUS Abstract 1994:290039 (1993) Ruggiero et al.

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