Use of phospholipase inhibitors in the treatment of Clostridium

Details Use of phospholipase inhibitors in the treatment of Clostridium Use of phospholipase inhibitors in the treatment of Clostridium

1986-05-02

1989-04-11

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514547, 514867, A61K 3144, A61K 31225

Patent

active

048207144

ABSTRACT:
Hemorrhagic fluid secretion and histologic damage to the intestinal mucosa by C. difficile toxin is blocked by the use of phospholipase inhibitors.

REFERENCES:
patent: 4239780 (1980-12-01), Wallach
Emeis J. J.; Kluft C., Blood, 1985, 66/1, (86-91).
Rao G. H. R.; White J. G., Agents Actions, 1985, 16/5, (425-434).
Parente L.; Flower R. J., Life Sci., 1985, 36/13, (1225-1231).
Peters S. P. et al., Respiration, 1986, 50/Suppl. 2, (116-122).
Maridonneau--Parini I.; Tauber A. I., Biochem. Biophys. Res. Comm., 1986, 138/3, (1099-1105).
Metz S. A., Diabetes, 1986, 35/7, (808-817).

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