Use of pervanadate as an inhibitor of phosphotyrosine phosphatas

Details Use of pervanadate as an inhibitor of phosphotyrosine phosphatas Use of pervanadate as an inhibitor of phosphotyrosine phosphatas

1990-06-07

1992-10-13

Naff, David M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Enzyme inactivation by chemical treatment

435244, C12N 999, C12N 138

Patent

active

051550318

ABSTRACT:
Disclosed is a method of inhibiting phosphotyrosine phosphatase activity on a substrate which comprises preincubating the substrate with a pervanadate-containing solution. Also disclosed is the use of a solution comprising pervanate as an inhibitor of phosphotyrosine phosphatases and as a regulator of cell growth.

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