Use of peptides in control of cell attachment and detachment

Details Use of peptides in control of cell attachment and detachment Use of peptides in control of cell attachment and detachment

1985-05-24

1989-11-07

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

43524021, 530331, C12N 500

Patent

active

048792373

ABSTRACT:
A method of using synthetic cell attachment-promoting peptides from fibronectin to detach cultured cells from the substratum is described.

REFERENCES:
patent: 4578079 (1986-03-01), Rouslahti et al.
Pierschbacher, M. D. et al., "Variants of the Cell Recognition Site of Fibronectin that Retain Attachment-Promoting Activity", P.N.A.S., vol. 81, (Oct. 1984), pp. 5985-5988.
Pierschbacher, M. D. et al., "Cell Attachment Activity of Fibronectin Can Be Duplicated by Small Synthetic Fragments of the Molecule", Nature, vol. 309, (May 3, 1984), pp. 30-33.
Effects of Fibronectin-Related Peptides on Cell Spreading Silnutzer, I. E. and Barnes, D. W., 1985, In Vitro, 21:73-78.
Isolation and Biological Characterization of Active Fragments of the Adhesive Glycoprotein Fibronectin, Hahn, L-H. E. and Yamada, K. M., (1979), Cell 18:1043-1051.
Substrate Adhesion of Rat Hepatocytes: on the Mechanism of Attachment to Fibronectin, Johansson et al., 1984, Cell Bilo., 98:810-817.

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