Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1981-06-30
1986-07-01
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 13, A61K 3702
Patent
active
045980659
ABSTRACT:
Certain peptides containing the glucagon.sub.1-21 peptide chain His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Al a-Gln-Asp, usable as a medicament or a diagnostic; the peptide exerts a spasmolytic effect and an inhibitory effect on gastric acid secretion similar to glucagon with not more than a negligible metabolic effect. Some of the glucagon fragments are novel compounds.
REFERENCES:
patent: 3642763 (1972-02-01), Wunsch et al.
patent: 3715345 (1973-02-01), Smith
patent: 3875138 (1975-04-01), Jackson
patent: 4221777 (1980-09-01), Nishino
Abiko et al., Chem. Pharm. Bull., 27(11), 2827-31 (1979).
Fujino et al., Chem. Pharm. Bull., 26(2), 539-548 (1978).
Wright et al., J. of Biological Chem., 253, 6338 (1978).
Frandsen et al., Hoppe-Seyler's Z. Physiol. Chem., 362, 665-675 (1971).
Jorgensen et al., European J. of Pharm., 90 (No. 4), 315-323 (1983).
Goldfine et al., J. of Biol. Chem., 247 (No. 4), 1211-1218 (1972).
Bromer, Metabolism Clinical and Experimental, XXV, 1315-16 (1976).
Schroder et al., The Peptides, II, Academic Press, N.Y., 254-260 (1966).
Chemical Abstracts, 70, 2028 (1969), Abst. No. 20330f.
Spiegel et al., Activity of Modified Glucogon, 85, 638-643 (1969).
Rodbell et al., Proc. Nat. Acad. Sci. USA, 68 (No. 5), 909-913 (1971).
Assan et al., Diabetes, 21 (No. 8), 843-855 (1972).
Epand et al., Canadian J. of Physiol. & Pharm. 51, 243-8 (1973).
Ross et al., Biochemistry, 16 (No. 24), 5398-5402 (1977).
Deranleau et al., J.A.C.S., 100: 6, 1913-1917 (1978).
Frandsen Erik K.
Gronvald Frederik C.
Johansen Nils L.
Jorgensen Karin D.
Lundt Behrend F.
Moezie F. T.
Novo Industri A/S
Phillips Delbert R.
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