Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition
Reexamination Certificate
2008-03-11
2009-10-27
Swartz, Rodney P. (Department: 1645)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Testing efficacy or toxicity of a compound or composition
C424S009100, C424S130100, C424S150100, C424S163100, C424S164100, C424S184100, C424S234100, C424S257100, C424S258100, C424S259100
Reexamination Certificate
active
07608247
ABSTRACT:
The present invention provides a method for the treatment and/or prevention of bacterial infection in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided is an antibody binding to OmpA that can assay OmpA levels in a biological sample and detect or diagnose bacterial infection in central nervous system and/or peripheral blood circulation.
REFERENCES:
patent: WO/93/25845 (1993-12-01), None
Wertz, J.E., et al. A molecular phylogeny of enteric bacteria and implications for a bacterial species concept. J. Evol. Biol., vol. 16, pp. 1236-1248, 2003.
Chen Mei-Ru
Hsieh Wen-Shyang
Huang I-Jen
Lee Chi-Hsin
Leu Sy-Jye
King Anthony
Swartz Rodney P.
Taipei Medical University
WPAT, P.C.
Yang Kay
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