Use of orthoesters for the synthesis of chiral acids in...

Details Use of orthoesters for the synthesis of chiral acids in... Use of orthoesters for the synthesis of chiral acids in...

2005-10-11

2005-10-11

Lilling, Herbert J. (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

C435S121000, C435S134000, C435S135000, C435S146000, C435S195000, C435S196000, C435S197000, C435S280000

Reexamination Certificate

active

06953678

ABSTRACT:
A process for the resolution of enantiomeric mixtures of a chiral carboxylic acid, including an esterification reaction of the carboxylic acid in an organic solvent, in the presence of a stereoselective hydrolase, characterized in that an orthoester of the formula R1—C(OR2)3, in which R1is selected from H and C1–C4alkyl and R2is C1–C8alkyl or —CH2—C6-10aryl, is used as the esterification reactive.

REFERENCES:
patent: 4107439 (1978-08-01), Walker et al.
patent: 4888433 (1989-12-01), Giordano et al.
patent: 5108916 (1992-04-01), Cobbs et al.
patent: 5302528 (1994-04-01), Battistel et al.
patent: 5580783 (1996-12-01), Sariaslani et al.
patent: 6166170 (2000-12-01), Putzig
patent: 6262288 (2001-07-01), Fehr et al.
patent: 6372929 (2002-04-01), Ridland et al.
patent: 0 407 033 (1991-01-01), None
patent: 0 510 712 (1992-10-01), None

Affiliated with

Also associated with

Rating

Use of orthoesters for the synthesis of chiral acids in... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of orthoesters for the synthesis of chiral acids in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of orthoesters for the synthesis of chiral acids in... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3447993