Use of octenidine dihydrochloride in semisolid preparations

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S944000, C514S967000, C424S404000, C424S405000, C424S422000, C424S430000

Reexamination Certificate

active

07846947

ABSTRACT:
The invention relates to the use of octenidine dihydrochloride for manufacturing a semisolid pharmaceutical composition for the treatment of wounds, atopic dermatitides, infected eczemas, dermatomycoses, vaginal infections, acne, herpes and/or for controlling multidrug-resistant pathogens, where the composition comprises from 0.005 to 5% by weight octenidine dihydrochloride, and a corresponding composition.

REFERENCES:
patent: 4614649 (1986-09-01), Gorman et al.
patent: 5176901 (1993-01-01), Gallopo et al.
patent: 6380391 (2002-04-01), Beilfuss et al.
patent: 27 08 331 (1977-09-01), None
patent: 39 25 540 (1990-08-01), None
patent: WO 0202128 (2002-01-01), None
patent: 2006/099359 (2006-09-01), None
Remington's Pharmaceutical Sciences, 15thEdition, 1975, Mack Publishing Company, p. 1244.
Sedlock et al., “Microbicidal Acitivity of Octenidine Hydrochloride, a New Alkanediylbis[Pyridine] Germicidal Agent,” Antimicrobial Agents & Chemotherapy, vol. 28, No. 6, pp. 786-790 (1985).
Friese et al., “Topical antiseptics as an alternative in the treatment of acule vulvovaginal candidosis,” Arc. of Gyn. & Obst., vol. 268, No. 3, pp. 194-197 (Aug. 2003).

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