Use of novel metalloporphyrins as imageable tumor-targeting...

Details Use of novel metalloporphyrins as imageable tumor-targeting... Use of novel metalloporphyrins as imageable tumor-targeting...

2005-10-04

2005-10-04

Hartley, Michael (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C424S001850, C534S010000, C534S014000, C534S015000, C514S185000

Reexamination Certificate

active

06951640

ABSTRACT:
The present invention covers halogenated derivatives of boronated phorphyrins containing multiple carborane cages having the formulawhich selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.

REFERENCES:
patent: 5877165 (1999-03-01), Miura et al.
patent: 6566517 (2003-05-01), Miura et al.
patent: 6759403 (2004-07-01), Miura et al.

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