Use of non-hybridizable nucleic acids for the detection of nucle

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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935 78, 436811, 436518, 435 7, C12Q 168, G01N 3353, G01N 33543

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active

047242027

ABSTRACT:
A detection probe comprising a hybridizable single stranded portion of nucleic acid connected with a non-hybridizable, single or double stranded nucleic acid portion, the non-hybridizable portion preferably including a recognition site for a particular protein.

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Annual Review of Biophysics and Bioengineering, vol. 10, 1981, "The Interaction of Intercalating Drugs with Nucleic Acids", Helen M. Berman and Peter R. Young, pp. 87-114.
Accounts of Chemical Research, vol. 11, 1978, "Platinum Complexes: Probes of Polynucleotide Structure and Antitumor Drugs", Stephen J. Lippard, pp. 211-217.

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