Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-06-26
2007-06-26
Chan, Christina (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007210, C530S387100, C530S387300, C530S388100, C530S388150, C530S388200
Reexamination Certificate
active
11329884
ABSTRACT:
The invention provides a novel NAIP nucleic and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
REFERENCES:
patent: 5919912 (1999-07-01), Korneluk et al.
patent: 6020127 (2000-02-01), MacKenzie et al.
patent: 6107041 (2000-08-01), Korneluk et al.
patent: 6156535 (2000-12-01), Korneluk et al.
patent: 6541457 (2003-04-01), Korneluk et al.
patent: 6656704 (2003-12-01), Korneluk et al.
patent: 6689562 (2004-02-01), Korneluk et al.
patent: 6977158 (2005-12-01), Korneluk et al.
patent: 2002/0137028 (2002-09-01), Korneluk et al.
patent: WO 94/06814 (1994-03-01), None
patent: WO 95/19431 (1995-07-01), None
patent: WO 96/12016 (1996-04-01), None
patent: WO 97/06255 (1997-02-01), None
Birnbaum et al., “An Apoptosis-Inhibiting Gene from a Nuclear Polyhedrosis Virus Encoding a Polypeptide with Cys/His Sequence Motifs,”J. Virol.68:2521-2528 (1994).
Campbell, “Monoclonal Antibody Technology,” Elsevier Science Publishers B.V. N.Y. NY. (1984).
Clem and Miller, “Induction and Inhibition of Apoptosis by Insect Viruses,” in “Apoptosis II: The Molecular Basis of Apoptosis in Disease,” Tomei and Cope (eds.), pp. 89-110 Cold Spring Harbor Press New York, NY, p. 89 (1994).
Clem et al., “Prevention of Apoptosis by a Baculovirus Gene During Infection of Insect Cells,”Science254:1388-1390 (1991).
Clem and Miller, “Control of Programmed Cell Death by the Baculovirus Genes P35 and lap,”Mol. Cell. Biol.14:5212-5222 (1994).
Clem et al., “Anti-Apoptotic Genes of Baculovirus,”Cell Death3:9 (1996).
Crook et al., “An Apoptosis-Inhibiting Baculovirus Gene with a Zinc Finger-Like Motif,”J. Virol.67:2168-2174 (1993).
Dhein et al., “Autocrine T-Cells Suicide Mediated by APO-1/(Fas/CD95),”Nature373:438-441 (1995). [Abstract].
Duckett et al., “A Conserved Family of Cellular Genes Related to the Baculovirus lap Gene and Encoding Apoptosis Inhibitors,”EMBO J.15:2685-2694 (1996).
Fernandez et al., “Differential Sensitivity of Normal and Ha-Ras-Transformed C3H Mouse Embryo Fibroblasts to Tumor Necrosis Factor: Induction of Bcl-2, C-Myc, and Manganese Superoxide Dismutase in Resistant Cells,”Oncogene9:2009-2017 (1994). [Abstract].
Ferrari et al., “N-Acetylcysteine (D- and L-Stereoisomers) Prevents Apoptotic Death of Neuronal Cells,”J. Neurosci.15:2857-2866 (1995). [Abstract].
Fisher et al., “Dominant Interfering Fas Gene Mutations Impair Apoptosis in a Human Autoimmune Lymphoproliferative Syndrome,”Cell81:935-946 (1995).
Gibellini et al., “Tat-Expressing Jurkat Cells Show an Increased Resistance to Different Apoptotic Stimuli, Including Acute Human Immunodeficiency Virus-Type 1 (HIV-1) Infection,”Br. J. Haematol.89:24-33 (1995). [Abstract].
Gilliam, “Is the Spinal Muscular Atrophy Gene Found?,”Nat. Med.1:124-127 (1995).
Golstein et al., “Homology Between Reaper and the Cell Death Domains of Fas and TNFR1,”Cell81:185-186 (1995).
Goruppi et al., “Dissection of C-Myc Domains Involved in S Phase Induction of NIH373 Fibroblasts,”Oncogene9:1537-1544 (1994). [Abstract].
Harrington et al., “c-Myc-Induced Apoptosis in Fibroblasts is Inherited by Specific Cytokines,”EMBO J.13:3286-3295 (1994). [Abstract].
Itoh and Nagata, “A Novel Protein Required fpr Apoptosis Mutational Analysis of Human Fas Antigen,”J. Biol. Chem.268:10932-10937 (1993). [Abstract].
Katsikis et al., “Fas Antigen Stimulation Induces Marked Apoptosis of T Lymphocytes in Human Immunodeficiency Virus-Infected Individuals,”J. Exp. Med.181:2029-2036 (1995). [Abstract].
Kerr, “Neglected Opportunities in Apoptosis Research,”Trends Cell Biol.5:55-57 (1995).
Korsmeyer, “Regulators of Cell Death,”Trends Genet.11:101-105 (1995).
Lerner, “Tapping the Immunological Repertoire to Produce Antibodies of Predetermined Specificity,”Nature299:592-596 (1982).
Lewin, “Genes for SMA: Multum in parvo,”Cell80:1-5 (1995).
Li et al., “Induction of Apoptosis in Uninfected Lymphocytes by HIV-1 Tat Protein,”Science268:429-431 (1995). [Abstract].
Liston et al., “Suppression of Apoptosis in Mammalian Cells by NAIP and a Related Family of IAP Genes,”Nature379:349-353 (1996).
Mahadevan et al., “SMA Genes: Deleted and Duplicated,”Nat. Genet.9:112-113 (1995).
Martin et al., “HIV-1 Infection of Human CD4+ T Cells In Vitro. Differential Induction of Apoptosis in These Cells,”J. Immunol.152:330-342 (1994). [Abstract].
Melino et al., “Tissue Transglutaminase and Apoptosis: Sense and Antisense Transfection Studies with Human Neuroblastoma Cells,”Mol. Cell. Biol.14:6584-6596 (1994). [Abstract].
Muro-Cacho et al., “Analysis of Apoptosis in Lymph Nodes of HIV-Infected Persons. Intensity of Apoptosis Correlates with the General State of Activation of the Lymphoid Tissue and not with Stage of Disease or Viral Burden,”J. Immunol.154:5555-5566 (1995). [Abstract].
Ngo et al., in “The Protein Folding Problem and Tertiary Structure Prediction,” Merz et al., (eds.) Birkhauser Boston: Boston, MA, pp. 433 and 492-495 (1994).
Nunez and Clarke, “The Bcl-2 Family of Proteins: Regulators of Cell Death and Survival,”Trends Cell Biol.4:399-403 (1994).
Osborne and Schwartz, “Essential Genes that Regulate Apoptosis,”Trends Cell Biol.4:394-399 (1994).
Rabizadeh et al., “Expression of the Baculovirus P35 Gene Inhibits Mammalian Neural Cell Death,”J. Neurochem.61:2318-2321 (1993). [Abstract].
Rieux-Laucat et al., “Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity,”Science268:1347-1349 (1995).
Rosenbaum et al., “Evidence for Hypoxia-Induced, Programmed Cell Death of Cultured Neurons,”Ann. Neurol.36:864-870 (1994). [Abstract].
Rothe et al., “The TNFR2-TRAF Signaling Complex Contains Two Novel Proteins Related to Baculoviral Inhibitor of Apoptosis Proteins,”Cell83:1243-1252 (1995).
Roy et al., “The Gene for Neuronal Apoptosis Inhibitory Protein is Partially Deleted in Individuals with Spinal Muscular Atrophy,”Cell80:167-178 (1995).
Sambrook et al., In “Molecular Cloning: A Laboratory Manual,” 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1989).
Sato et al., “Neuronal Differentiation of PC12 Cells as A Result of Prevention of Cell Death by Bcl-2,”J. Neurobiol.25:1227-1234 (1994). [Abstract].
Scharf et al., “The Mouse Region Syntenic for Human Spinal Muscular Atrophy Lies Within the Lgn1 Critical Interval and Contains Multiple Copies of Naip Exon 5,”Genomics38:405-417 (1996).
Skolnick and Fetrow, “From Genes to Protein Structure and Function: Novel Applications of Computational Approaches in the Genomic Era,”Trends Biotechnol.18:34-39 (2000).
Steller, “Mechanisms and Genes of Cellular Suicide,”Science267:1445-1449 (1995).
Talley et al., “Tumor Necrosis Factor α-Induced Apoptosis in Human Neuronal Cells: Protection by the Antioxidant N-Acetylcysteine and the Genes Bcl-2 and CrmA,”Mol. Cell. Biol.15:2359-2366 (1995). [Abstract].
Terai et al., “Apoptosis as a Mechanism of Cell Death in Cultured T Lymphoblasts Acutely Infected with HIV-1,”J. Clin. Invest.87:1710-1715 (1991). [Abstract].
Vossbeck et al., “Direct Transforming Activity of TGF-β on Rat Fibroblasts,”Int. J. Cancer61:92-97 (1995). [Abstract].
Walkinshaw et al., “Induction of Apoptosis in Catecholaminergic PC12 Cells by L-DOPA. Implications for the Treatment of Parkinson's Disease,”J. Clin. Invest.95:2458-2464 (1995). [Abstract].
Wallace and Miyada, “Oligonucleotide Probes for the Screening of Recombinant DNA Libraries,”Methods Enzymol.152:432-442 (1987).
We
Korneluk Robert G.
MacKenzie Alexander E.
Robertson George
Roy Natalie
Tamai Katsu
Chan Christina
Gowling Lafleur Henderson LLP
Huynh Phuong
Swain Philip A.
University of Ottawa
LandOfFree
Use of neuronal apoptosis inhibitor protein (NAIP) does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of neuronal apoptosis inhibitor protein (NAIP), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of neuronal apoptosis inhibitor protein (NAIP) will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3845697