Use of neuronal apoptosis inhibitor protein (NAIP)

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S069100, C435S320100, C435S366000, C435S388000, C530S350000, C536S063000

Reexamination Certificate

active

06994957

ABSTRACT:
The invention provides NAIP nucleic acid and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis.

REFERENCES:
patent: WO 94/06814 (1994-03-01), None
patent: WO 95/19431 (1995-07-01), None
Ngo et al, in The Protein Folding Problem and Tertiary Structure Prediction, 1994, Merz, et al., (ed.), Birkhauser, Boston, MA, pp. 433 and 492-495.
Skolnick et al, From genes to protein structure and function: novel applications of computational approaches in the genomic era, Jan. 2000, Trends in Biotech. 18(1): 34-39.
Wallace et al, Ologonucleotide Probes for the screening of recombinant DNA libraries, 1987, Methods Enzymol 152: 432-443.
Sambrook et al, in Molecular Cloning A laboratory manual, 1989 second edition.
Lewin, B, Genes for SMA: Multum in parvo. Cell, 80:1-5, Jan. 13, 1995.
Bimbaum et al., “An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs”, J. of Virol. 68:2521 (1994).
Bimbaum et al., “An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs”, Abstract, J. Virol. 68:2521 (1994).
Campbell, Monoclonal Antibody Technology, Elsevier Science Publishers B.V. N.Y. NY. (1984).
Clem et al., “Induction and inhibition of apoptosis by insect viruses”, Apoptosis II: The Molecular Basis of Apoptosis in Disease, Cold Spring Harbor Laboratory Press, p. 89, (1994).
Clem et al., “Anti-apoptotic genes of baculovirus”, Cell Death and Differentiation, 3: 9-16, (1996).
Clem et al., “Prevention of apoptosis by a baculovirus gene during infection of insect cells”, Science 254:1388, (1991).
Clem et al., “Control of programmed cell death by the baculovirus genes p35 and iap”, Mol. and Cell. Biology 14:5212, (1994).
Crook et al., “An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif”, J. of Virol. 67:2168, (1993).
Dhein et al., “Autocrine T-cells suicide mediated by APO-1(Fas/CD95)”, Abstract, Nature 373:438, (1995).
Duckett et al., “A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors”, The EMBO Journal, 15: 2685-2694, (1996).
Fernandez et al., “Differential sensitivity of normal and Ha-ras-transformed C3H mouse embryo fibroblasts to tumor necrosis factor: . . . ”, Abstract, Oncogene 9:2009, (1994).
Ferrari et al., “N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells”, Abstract, J. Neurosci. 1516:2857, (1995).
Fisher et al., “Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome”, Cell 81:935, (1995).
Gibellini et al., “Tat-expressioon Jurkat cells show an increased resistance to different apoptic stimuli . . . ”Abstract, Br. J. Haematol 89:24, (1995).
Golstein et al., “Homology between reaper and the cell death domains of Fas and TNFR1”, Cell 81:185, (1995).
Goruppi et al., “Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts”, Abstract, Oncogene 9:1537, (1994).
Harrington et al., “c-Myc-induced apoptosis in fibroblasts is inherited by specific cytokines”, Abstract, EMBO J. 13:3286, (1994).
Itoh et al., “A novel protein required for apoptosis . . . ”, Abstract, J. Biol. Chem. 268:10932, (1993).
J. Kerr, “Neglected opportunities in apoptosis research”, Trends in Cell Biology 5:55, (1995).
Katsikis et al., “Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals”, Abstract, J. Exp. Med. 1815:2029, (1995).
Korsmeyer, “Regulators of cell death”, TIG 11:101, (1995).
Lerner, Nature, 299:592-596, (1982).
Li et al., “Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein”, Abstract, Science 268:429, (1995).
Liston et al., “Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes”, Nature, 379: 349-353, (1996).
Martin et al., “HIV-1 infection of human CD4+ T cells in vitro . . . ”, Abstract, J. Immunol. 152:330, (1994).
Melino et al., “Tissue transglutaminase and apoptosis: sense and antisense transfection studies . . . ”Abstract, Mol. Cell. Biol. 14:6584, (1994).
Muro-Cacho et al., “Anlaysis of apoptosis in lymph nodes of HIV-infected persons . . . ”, Abstract, J. Immunol. 154:5555, (1995).
Nunez et al., “The Bcl-2 family of proteins: regulators of cell death and survival”, Trends in Cell Biology 4:399, (1994).
Osborne et al., “Essential genes that regulate apoptosis”, Trends in Cell Biology 4:394, (1994).
Rabizadeh et al., “Expression of the baculovirus p35 gene inhibits mammalian neural cell death”, Abstract, J. Neurochem. 61:2318, (1993).
Rieux-Laucat et al., “Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity”, Science 268:1347, (1995).
Rosenbaum et al., “Evidence for hypoxia-induced, programmed cell death of cultured neurons”, Abstract, Ann. Neurol. 36:864, (1994).
Rothe et al., “The TNFR2-TRAF Signaling Complex Contains Two Novel Proteins Related to Baculoviral Inhibitor of Apoptosis Proteins”, Cell, 83: 1243-1252, (1995).
Roy et al., “The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy”, Cell 80:167, (1995).
Sato et al., “Neuronal differentiation of PC12 cells as a result of prevention of cell death by bcl-2”, Abstract J. Neurobiol. 25:1227, (1994).
Steller, “Mechanisms and Genes of Cellular Suicide”, Science 267:1445, (1995).
Talley et al., “Tumor necrosis facor alpha-induced apoptosis in human neuronal cells: . . . ”, Abstract, Mol. Cell. Biol. 1585:2359, (1995).
Terai et al., “Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1” Abstract, J. Clin. Invest 87:1710, (1991).
Vossbeck et al., “Direct transforming activity of TGF-beta on rat fibroblasts”, Abstract, Int. J. Cancer 61:92, (1995).
Westendorp et al., “Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120”, Nature 375:497, (1995).
Walkinshaw et al., “Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA . . . ”, Abstract, J. Clin. Invest. 95::2458, (1995).
White et al., “Genetic control of programmed cell death in drosophila”, Science 264:677, (1994).
Williams et al., “ Apoptosis: final control point in cell biology”, Trends in Cell Biology 2:263, (1992).
Wyllie, “Death gets a brake”, Nature 369:272, (1994).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of neuronal apoptosis inhibitor protein (NAIP) does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of neuronal apoptosis inhibitor protein (NAIP), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of neuronal apoptosis inhibitor protein (NAIP) will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3638843

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.