Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1995-06-06
1998-05-19
Stone, Jacqueline M.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4351723, 4352401, 4353201, 43524025, 514 44, 424 9321, A61K 4800, C12N 500, C12N 1500
Patent
active
057534918
ABSTRACT:
The present invention generally relates to methods for treating a host by implanting genetically unrelated cells in the host. More particularly, the present invention provides human fetal neuro-derived cell lines, and methods of treating a host by implantation of these immortalized human fetal neuro-derived cells into the host.
REFERENCES:
patent: 4707448 (1987-11-01), Major
patent: 4892538 (1990-01-01), Acbischer et al.
patent: 5032407 (1991-07-01), Wagner et al.
patent: 5082676 (1992-01-01), Gage et al.
Bankiewicz et al., "The effect of fetal mesencephalon implants on primate MPTP-induced parkinsonism," J. Neurosurg. 72:231-244.
Bjorkland et al., "Reconstruction of the Nigrostriatal dopamine pathway by intracerebral Nigral transplants," Brain Res. 177:555-560 (1979).
Brundin, "Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival," Brain Res., 331:251-259 (1985).
Cattaneo, "Identifying and manipulating neuronal stem cells," Trends in Neurosci. 14:338-340 (1991).
Fisher et al., "Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-Dopa," Neuron 6:371-380 (1991).
Freed, "Substantia nigra grafts and Parkinson's disease: from animal experiments to human therapeutic trials," Restor. Neurol. Neurosci. 3:109-134 (1991).
Gage et al., "Intracerebral grating: a tool for the neurobiologist," Neuron6:1-12 (1991).
Lendahl, "The use of cell lines in neurobiology," Trends in Neurosci. 13:132-137 (1990).
Lindvall et al., "Human fetal dopamine neurons surivive and improve motor function in Parkinson's disease," Science247:574-577 (1990).
Lindvall et al., "Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease," Arch. Neurol. 46:615-631 (1989).
Major et al., "Establishment of a line of human fetal glial cells that supports JC virus multiplication," Proc. Nat'l Acad. Sci. USA82: 1257-1262 (1985).
Noel et al., "A method for large-scale high-yield isolation of canine pancreatic Islets of Langerhans," Metabolism31:184-187 (1992).
Plunkett et al., "Implantation of dispersed cells into primate brain," J. Neurosurg. 70:441-445 (1989).
Rosenberg et al., "Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression," Science242:1575-1577 (1988).
Sun et al., "Microencapsulated Hepatocytes: an in vitro and in vivo study," Biomat., Art. Cells, Art Org., 15:483-496 (1987).
Taylor et al., "Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys," Prog. Brain. Res. 82:543-559. (1990.
Tornatore et al., "Implantation and survival of a human fetal astrocyte cell line in the basal ganglia of the non-human primate, rhesus monkey," J. of Cellular Biochemistry, Abstract Supp. 17E (Keystone Symposium on Gene Therapy, Apr. 12-18, 1993) New York, NY, p. 227, Abstract SZ 115.
Uchida et al., "Transfection of tyrosine hydroxlase CDNA into C6 cells. The synthesis and release of L-DOPA," 3-Biochem. Genetics 110(11):207 (1989) Abstract No. 110:89851p.
Widner et al., "Biolateral fetal mesencephalic grafting in two patients with Parkinsonism induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)," New Eng. J. Med.327:1556-1563 (1992).
Windner and Brundin, "Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis," Brain Res. Rev.13:287-324 (1988).
Wolff et al., "Grafting fibroblasts genetically modified to produce L-dopa in a rat model of parkinson's disease," Proc. Nat'l Acad. Sci. USA 86:9011-9014 (1989).
Marshall, Science, 269, 1995, 1050-1055.
Culver et al., TIG, 10(5), 1994, 174-178.
Miller et al., Faseb J., 9, 190-199, 1995.
Hodgson, Exp. Opin. Ther. Pat., 5(5), 1995, 459-468.
Major Eugene O.
Tornatore Carlo S.
Yadid Gal
Milne Andrew
Stone Jacqueline M.
LandOfFree
Use of neuro-derived fetal cell lines for transplantation therap does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of neuro-derived fetal cell lines for transplantation therap, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of neuro-derived fetal cell lines for transplantation therap will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1852176