Use of N-low-alkyl glycines, their acid amides and of sarcosine

Details Use of N-low-alkyl glycines, their acid amides and of sarcosine Use of N-low-alkyl glycines, their acid amides and of sarcosine

1986-05-08

1988-08-23

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 31135

Patent

active

047661496

ABSTRACT:
Sarcosine and certain sarcosine derivatives, specifically N-low alkyl glycines with 1 to 4 carbon atoms in the N-alkyl part, their acid amides and sarcosine anhydride exhibit a tumor-inhibiting effect alone for themselves and mixed with one another, as well as a synergistic effect in combination with other tumor-inhibiting compounds, in particular antineoplastic alkylating compounds, intercalating substances, antimetabolites and plant substances.

REFERENCES:
Field et al., Cancer Research, Supplement No. 2, 1955, pp. 3-5 and 31.
The Merck Index, 9th ed, Merck & Co., Inc., Rahway, N.J., 1976 p. 359.

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