Use of N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethyldithi

Details Use of N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethyldithi Use of N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethyldithi

1982-10-21

1984-05-08

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23366

Patent

active

044476213

ABSTRACT:
A process for preparing cimetidine by sulfur extrusion from N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethyldithio)ethyl]guanidine .

REFERENCES:
patent: 3950333 (1976-04-01), Durant et al.
patent: 4013678 (1977-03-01), Brown et al.
Harpp et al., J. Org. Chem., 35, No. 10, pp. 3259-3263 (1970).
Reid, "Organic Chemistry of Bivalent Sulphur", vol. I. p. 124 (1958).
DeMarinis et al., J. Org. Chem., 42:2024-2025 (1977).
Harpp et al., J. Am. Chem. Soc., 93:2437-2445 (1971).

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