Use of N-arylmethylene ethylenediaminetriacetates N-arylmethylen

Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing

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560 17, 560 38, 560 39, 560 22, 562426, 562435, 562443, 562449, 562453, C07F 1502, C07C22924

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active

056294360

ABSTRACT:
N-arylmethylene ethylenediaminetriacetate, N-arylmethylene iminodiacetate or N,N'-diarylmethylene ethylenediaminediacetate type compounds and their use in combatting oxidative stress, and pharmaceutical and cosmetic compositions comprising said compounds. The invention also concerns a process for the preparation of said compounds.

REFERENCES:
patent: 4528196 (1985-07-01), Pitt
American Journal of Hematology, vol. 24, No. 3, Mar. 1987, pp. 277-284.
Inorganica Chimica Acta, vol. 138, No. 3, 1987, pp. 215-230.
Chemical Abstracts, vol. 110, No. 3, 27 Mar. 1989, No. 110927.
Pitt, C.G., et al, "Esters and Lactones of Phenolic Amino Carboxylic Acids: Prodrugs for Iron Chelation", J. Med. Chem., vol. 29, No. 7, Jul. 1986, pp. 1231-1237.

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