Use of N-acetyl-cysteine and derivatives for regulating skin wri

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 3123

Patent

active

052965007

ABSTRACT:
The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of N-acetyl-L-cysteine and/or a derivative thereof.

REFERENCES:
patent: 3242052 (1966-03-01), Sheffner
patent: 3591686 (1971-07-01), Sheffner
patent: 3647834 (1972-03-01), Martin
patent: 3749770 (1973-07-01), Martin
patent: 4016287 (1977-04-01), Eberhardt et al.
patent: 4132803 (1979-01-01), Martin
patent: 4139610 (1979-02-01), Miyazaki et al.
patent: 4276284 (1981-06-01), Brown
patent: 4331648 (1982-05-01), Myers, Jr. et al.
patent: 4411886 (1983-10-01), Hostettler et al.
patent: 4708965 (1987-11-01), Morgan
patent: 4711780 (1987-12-01), Fahim
patent: 4721705 (1988-01-01), Schreuder
patent: 4724239 (1988-02-01), Morgan
patent: 4827016 (1989-05-01), Morgan
patent: 4859653 (1989-08-01), Morelle et al.
patent: 4868114 (1989-09-01), Nagasawa et al.
patent: 4876283 (1989-10-01), Reichert
CA Selects: Cosmetic Chemicals, Issue 1, (1993), p. 7, 117:257989e.
Gavish, D. and Breslow, J. L., "Lipoprotein(a) Reduction by N-acetylcysteine", The Lancet, vol. 337, pp. 203-204 (1991).
Karg, E., Tunek, A., Brotel, Rosenbren, E. and Rorsman, H., "Alteration of Glutathione Level in Human Melanoma Cells: Effect of N-Acetyl-L-Cysteine and its Analogues", Pigment Cell Research, vol. 3, pp. 11-15 (1990).
Staal, F. J. T., Roederer, M., Herzenberg, L. A. and Herzenberg, L. A., "intracellular Thiols Regulate Activation of Nuclear Factor kB and Transcription of Human Immunodeficiency Virus", Proceedings National Academy of Science, vol. 87, pp. 9943-9947 (1990).
Rougee, M., Bensasson, R. V., Land, E. J. and Pariente, R, "Deactivation of Singlet Molecular Oxygen by Thiols and Related Compounds, Possible Protectors Against Skin Photosensitivity", Photochemistry and Photobiology, vol. 47, pp. 485-489 (1988).
Kligman, L. H., "Effects of All-trans-retinoic Acid on the Dermis of Hairless Mice", Journal of the American Academy of Dermatology, vol. 15, pp. 779-785 (1986).
Isom, G. E. and Kildsig, D. O., "Targeted Drug Carriers: Biological Activity of the N-acetylcysteine-liposome System", Methodol. Surv. Biochem. Anal., vol. 13, pp. 331-336 (1984).
Verhey, L. and Sedlacek, R., "Determination of the Radioprotective Effects of Tropical Applications of MEA, WR-2721, and N-acetylcysteine on Murine Skin", Radiation Research, vol. 93, pp. 175-183 (1983).
Reyniers, P., Broekaert, D., Coucke, P., Nsabumukunzi, S., Klyskens and Gillis, E., "The Evaluation of New Methods for Extraction of Keratins from Epidermis", Arch. Int. Physiol. Biochim., vol. 88(3), p. B146 (1980).
Kan, D., Gruber, C., Watford, A., Seifter, E. and Levenson, S. M., "Chemical Debridement of Burns with N-acetylcysteine", Surg. Forum, vol. 30, pp. 48-50 (1979).
Portelli, M., Renzi, G. and Cervato, G. "Synthesis of N-acetylcysteine Compounds", I1 Farmaco, vol. 31, pp. 767-775 (1976).
Kahn, G. and Curry, M. C., "Ultraviolet Light Protection by Several New Compounds", Arch. Dermatol., vol. 109, pp. 510-517 (1974).
Bartek, M. J. and LaBudde, J. A., "Percutaneous Absorption, In Vitro", Anim. Models Dermatol.: Relevance Hum. Dermatopharmacol. Dermatoxicol., E. by: Howard Maibach, pp. 103-120 (1975).
Bailey, K. R. and Sheffner, A. L., "The Reduction of Experimentally Induced Inflammation by Sulfhydryl Compounds", Biochemical Pharmacology, vol. 16, pp. 1175-1182 (1967).
"Farmacos Individuales/Single Drugs-N-acetylcysteine", Medicamentos de Actualidad, vol. 16, pp. 41-43 (1980).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of N-acetyl-cysteine and derivatives for regulating skin wri does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of N-acetyl-cysteine and derivatives for regulating skin wri, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of N-acetyl-cysteine and derivatives for regulating skin wri will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-437380

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.