Use of N 2 O in the treatment of post-ischemic brain cell...

Details Use of N 2 O in the treatment of post-ischemic brain cell... Use of N 2 O in the treatment of post-ischemic brain cell...

2004-01-15

2008-07-29

Pak, John (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated inorganic nonactive ingredient or elemental...

Oxygen gas containing

C128S203120, C604S023000

Reexamination Certificate

active

07405241

ABSTRACT:
A medicinal composition and method to treat or minimize post-ischemic brain cell deterioration that comprises nitrous oxide or a nitrous oxide donor and xenon or a xenon donor. The medicinal composition may be administered prior to or subsequent to a stroke.

REFERENCES:
patent: 3876773 (1975-04-01), Bracken
patent: 4820258 (1989-04-01), Mondain-Monval
patent: 0 861 672 (1998-09-01), None
patent: 2 812 545 (2002-02-01), None
patent: WO 93/06869 (1993-04-01), None
patent: WO 02 09731 (2002-02-01), None
Websters New World Dictionary Victoria Neufeldt ed. New York pp. 1067-1068.
Homi et al. The Neuroprotective effect of Xenon Administration during Transient Middle Cerebral Artery Occlusion in Mice Anesthesiology 2003, 99, 876-881.
Jevtovic-Todorovic et al. Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin Nature Medicine 1998, 4 (4), 460-463.
Kotwica et al. (Res. Exp. Med 1991, 191, 99-104).
Tonner et al. (Best Practice Research Clinical Anaesthesiology 2001, 15(3) 491-503).
French Search Report for FR 0350002.
Wang and Corbett, Brain Res., 533: 78, 1990.
Baldwin et al., Neurodegeneration 2: 139, 1993.
Chazot, Curr Opin Invest Drugs 1: 370, 2000.
Drian et al., Neurochem Int 38: 509, 2000.
Dirnagl et al., Trends Neurosci 22: 391, 1999.
Benes, Brain Res. Review 31: 251, 2000.
Burns et al., Psychopharmacology 115: 516, 1994.
Palmer and Widzowski, Amino acids 19: 151, 2000.
Franks et al., Nature 396: 324, 1998.
Jevtovic-Todorovic et al., Nature Med. 4: 460, 199.
Yamakura and Harris, Anesthesiology, 20008.

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