Use of multiple antioxidant micronutrients as systemic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S251000, C514S184000, C514S393000, C514S350000, C514S167000, C514S474000, C514S458000, C514S440000, C514S552000, C514S276000, C514S562000, C514S494000, C514S574000, C514S763000

Reexamination Certificate

active

07449451

ABSTRACT:
Disclosed herein is a method for protecting humans in need of such protection from physical damage caused by ionizing radiation comprising administering to said humans on a defined basis prior to and after exposure to such radiation a plurality of antioxidants at a dosage level directly proportional to the radiation level likely to be encountered.

REFERENCES:
patent: 2939821 (1960-06-01), Freedman et al.
patent: 3446899 (1969-05-01), Magid et al.
patent: 3584114 (1971-06-01), Cavalli
patent: 3777029 (1973-12-01), Magid
patent: 4619829 (1986-10-01), Motschan
patent: 4740373 (1988-04-01), Kesselman et al.
patent: 4976960 (1990-12-01), Grossman et al.
patent: 5084482 (1992-01-01), Hirsch et al.
patent: 5223285 (1993-06-01), DeMichele et al.
patent: 5292538 (1994-03-01), Paul et al.
patent: 5571441 (1996-11-01), Andon et al.
patent: 5626883 (1997-05-01), Paul
patent: 5629023 (1997-05-01), Bland
patent: 5788971 (1998-08-01), Togasaki
patent: 5922346 (1999-07-01), Hersh
patent: 5922704 (1999-07-01), Bland
patent: 5939394 (1999-08-01), Fleming et al.
patent: 5948823 (1999-09-01), Ben-Amotz
patent: 5976568 (1999-11-01), Riley
patent: 5985339 (1999-11-01), Kamarei
patent: 6048846 (2000-04-01), Cochran
patent: 6066327 (2000-05-01), Gubernick
patent: 6068848 (2000-05-01), Gubernick
patent: 6080788 (2000-06-01), Sole et al.
patent: 6090414 (2000-07-01), Passwater et al.
patent: 6117872 (2000-09-01), Maxwell et al.
patent: 6124268 (2000-09-01), Ghosad
patent: 6130244 (2000-10-01), DeMichele et al.
patent: 6162468 (2000-12-01), Stanley et al.
patent: 6194452 (2001-02-01), Murad
patent: 6245360 (2001-06-01), Markowitz
patent: 6254898 (2001-07-01), Bragaglia
patent: 6255341 (2001-07-01), DeMichele et al.
patent: 6258384 (2001-07-01), Stanley et al.
patent: 6291533 (2001-09-01), Fleischner
patent: 6326034 (2001-12-01), Mirsky et al.
patent: 6329414 (2001-12-01), Thomas et al.
patent: 6362167 (2002-03-01), Ghosal
patent: 6379664 (2002-04-01), Lou et al.
patent: 6426076 (2002-07-01), Pascoe
patent: 6426362 (2002-07-01), Miller et al.
patent: 6444221 (2002-09-01), Shaprio
patent: 6444700 (2002-09-01), DeMichele et al.
patent: 6451341 (2002-09-01), Slaga et al.
patent: 6573299 (2003-06-01), Petrus
patent: 6579544 (2003-06-01), Rosenberg et al.
patent: 6602512 (2003-08-01), Cavazza
patent: 6632459 (2003-10-01), Graus et al.
patent: 6660293 (2003-12-01), Giordano et al.
patent: 6753325 (2004-06-01), Rosenbloom
patent: 6770663 (2004-08-01), Wagle et al.
patent: 6797729 (2004-09-01), Byrne et al.
patent: 6805880 (2004-10-01), Højgaard et al.
patent: 6814983 (2004-11-01), Giordano et al.
patent: 6844012 (2005-01-01), Forceville et al.
patent: 6849613 (2005-02-01), Prasad et al.
patent: 6863904 (2005-03-01), Giordano et al.
patent: 2002/0146463 (2002-10-01), Clayton
patent: 2002/0182196 (2002-12-01), McCleary
patent: 2002/0182585 (2002-12-01), Kindness et al.
patent: 2002/0193323 (2002-12-01), Yegorova
patent: 2003/0055012 (2003-03-01), Carter
patent: 2003/0103954 (2003-06-01), Rosenbloom
patent: 2003/0104080 (2003-06-01), Singh
patent: 2003/0105027 (2003-06-01), Rosenbloom
patent: 2003/0108624 (2003-06-01), Kosbab
patent: 2003/0119909 (2003-06-01), Stanislaus
patent: 2003/0147981 (2003-08-01), Gillam
patent: 2003/0161863 (2003-08-01), Ballevre et al.
patent: 2003/0215430 (2003-11-01), Petrus
patent: 2004/0043013 (2004-03-01), McCleary
patent: 2004/0082536 (2004-04-01), Cooper et al.
patent: 2004/0106674 (2004-06-01), Rich et al.
patent: 2004/0109882 (2004-06-01), Schonrock
patent: 2004/0223962 (2004-11-01), Riordan
patent: 2005/0009779 (2005-01-01), Kiliaan et al.
“Anti-Irradiation Effect of Beta-Carotene and Vitamin E”, Chen et al., Zhonghua Fangshe Yixue Yu Zazi, 1997, 17(2), 117-119, abstract.
“Cysteine”, University of Maryland Medical Center, 2002.
“Multiple Myeloma”, www.merck.com, 2003.
“Baylor, St. Luke's study uses gene therapy as treatment for pancreatic cancer”, www.bcm.edu, 2006.
Cecil Textbook of Medicine, 20th Edition, vol. 1, 1997.
Niki, E.; Mechanisms and dynamics of antioxidant action of ubiquinol. Mol Aspects Med. 18 Suppl:S63-70; 1997. (Abstract).
Jacob, S., Henriksen, L, et. al. (1995) Enhancement of glucose disposal in patients with type II diabetes by alpha-lipoic acid. Arzneim Forsch, 45: 872-874. (Abstract).
Suzuki YJ, Tsuchiya M, Packer L: Lipoate prevents glucose-induced protein modifications. Free Rad Res Commun 17:211-217, 1992. (Abstract).
Verlangieri, A. J., Bush, M. J.; Effects of d-alpha-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr. 11:131-138; 1992. (Abstract).
Hoogwerf, B. J., Young, J. B.; The Hope study. Ramipril lowered cardiovascular risk, but vitamin E did not. Cleve Clin J Med. 67:287-293; 2000. (Abstract).
Carter, C. A., Pogribny, M., Davidson, A., Jackson, C. D., McGarrity, L. J., Morris, S. M.; Effects of retionic acid on cell differentiation and recersion toward normal in human endometrial adenocarcinoma (RL95-2) cells. Anticancer Res. 16:17-24; 1996. (Abstract).
Salonen, J. T.; Clinical trials testing cardiovascular benefits of antioxidant supplementation. Free, Radic Res. 36:1299-1306; 2002. (Abstract).
International Council for Radiation Protection, ICRP publication 33, 1982.
FDA Centers for Radiologic Health Handbook: Selected Tissue Doses for Fluoroscopic and Cineangiographic Examination of the Coronary Arteries, 1995.
FDA and Mayo Clinic values of X-ray doses, www.mayohealth.org, Mayo Foundation for Medican Education and Research (2000).
Gopalakrishna, R., Gundimeda, U., Chen, Z. Vitamin E Succinate Inhibits Protein Kinase C: Correlation With Its Unique Inhibitory Effects On Cell Growth And Transformation. In: Prasad, K. N., Santamaria, L., Williams, R. M., eds. Nutrients In Cancer Prevention And Treatment. Totowa, New Jersey: Humana Press; 1995:21-37.
Frei, B.,Natural Antioxidants in Human Health and Disease, Academic Press (1994).
Tasinato, A., Boscoboinik, D., Bartoli, G. M., Maroni, P., Azzi, A.; d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs as physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties. Proc Natl Acad Sci U S A. 92:12190-12194; 1995.
Radi, R.,Nitric oxide, oxidants, and protein tyrosine nitration, The National Academy of Sciences of the USA (2004).
Tardif, J. C., Cote, G., Lesperance, J., Bourassa, M., Lambert, J., Doucet, S., Bilodeau, L., Nattel, S., de Guise, P.; Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group. N Engl J Med. 337:365-372; 1997.
Brown, B.G. et al.,Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease, N Engl J Med 345:1583-1592; 2001.
Matthan, N.R. et al., Impact of Simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL, Journal of Lipid Research 44:800-806; 2003.
Gandhi VM, Wagh SS, Natraj CV, Menon KKG: Lipoic acid and diabetes II: mode of action of lipoic acid. J Biosci 9:117-127, 1985.
Earnest, C.P. et al., Complex Multivitamin Supplementation Improves Homocysteine and Resistance to LDL-C Oxidation, Journal of the American College of Nutrition 22:400-407; 2003.
Waters, D. D., Alderman, E. L., Hsia, J., Howard, B. V., Cobb, F. R., Rogers, W. J., Ouyang, P., Thompson, P., Tardif, J. C., Higginson, L., Bittner, V., Steffes, M., Gordon, D. J., Proschan, M., Younes, N., Verter, J. I.; Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial. Jama. 288:2432-2440; 2002.
Schnyder, G., Roffi, M., Flammer, Y., Pin, R., Hess, O. M.; Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial. JAMA. 288:973-979; 2002.
Haugaard, N, Haugaard ES: Stimulation of glucose utilization by thioctic acid in rat diaphragm inc

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