Use of monoacyl phosphoglycerides to enhance the corneal penetra

Details Use of monoacyl phosphoglycerides to enhance the corneal penetra Use of monoacyl phosphoglycerides to enhance the corneal penetra

1991-02-07

1993-06-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Carboxylic acid ester

514 78, 514788, 514912, 514947, A61K 4700, A61K 31685

Patent

active

052216969

ABSTRACT:
The use of monoacyl phosphoglycerides to enhance the penetration of topically applied ophthalmic drugs through the corneal epithelium is described.

REFERENCES:
"Permeability of Rabbit Corneal Epithelium to Horseradish Peroxidase After the Influence of Benzalkonium Chloride," Tonjum, Acta Ophthalmologica, vol. 53, pp. 335-347 (Jan., 1975).
"Evaluation of Permeability Enhancement of Hydrophilic Compounds and Macromolecular Compounds by Bile Salts Through Rabbit Corneas In Vitro," Morimoto, J. Pharm. Pharmacol., 39: 124-126 (Jul., 1986).
"Ophthalmic Compositions Containing Biphenamine and Their Use in the Treatment or Prevention of Inflammation," Schulte, Chemical Abstracts, 106: 125931t, vol. 106 (1987).
"Mechanisms of corneal Drug Penetration 1: In Vivo and In Vitro Kinetics," Grass, Journal of Pharmaceutical Sciences, vol. 77, No. 1., (Jan. 1988).
"Topically Applied Cyclosporine in Azone Prolongs Corneal Allograft Survival," Newton et al., Investigative Ophthalmology and Visual Science, vol. 29, No. 2, pp. 208-215 (Feb., 1988).

Affiliated with

Also associated with

Rating

Use of monoacyl phosphoglycerides to enhance the corneal penetra does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of monoacyl phosphoglycerides to enhance the corneal penetra, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of monoacyl phosphoglycerides to enhance the corneal penetra will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1441358