Use of microphthalmia for diagnosis, prognosis and/or...

Details Use of microphthalmia for diagnosis, prognosis and/or... Use of microphthalmia for diagnosis, prognosis and/or...

2008-03-04

2008-03-04

Ungar, Susan (Department: 1642)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007210, C435S007230

Reexamination Certificate

active

09229283

ABSTRACT:
Microphthalmia (Mi) while present in melanocytes, a cells and osteoclast, is not normally present in other cells. We have found that Mi is present in the nucleus of melanoma cells. Melanoma can be diagnosed by contacting a malignant cell with a probe for Mi. If the probe identifies Mi in the nucleus of the cell, the cell is a melanoma.

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