Use of methionine synthase inhibitors for the treatment of...

Details Use of methionine synthase inhibitors for the treatment of... Use of methionine synthase inhibitors for the treatment of...

2011-06-07

2011-06-07

Fronda, Christian L (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

C435S189000, C435S252300, C435S320100, C514S789000, C536S023200

Reexamination Certificate

active

07955828

ABSTRACT:
The invention relates to the use of methionine synthase inhibitors for the treatment of fungal diseases of crops. The invention further relates to methods for treatment of crops against fungal diseases comprising the application of a methionine synthase inhibitor also methods for the identification of novel fungicidal compounds comprising a step for identification of methionine synthase inhibitors.

REFERENCES:
patent: PCT/US2004/191849 (2004-09-01), None
Pacson et al. Microbiology. Sep. 2004;150(Pt 9):3013-23.
Pascon, Renata C. et al.: “Cryptococcus Neoformans Methionine Synthase: Expression Analysis and Requirement for Virulence” Microbiology (Reading), vol. 150, No. Part 9, Sep. 2004, pp. 3013-3023, XP002346120, ISSN: 1350-0872.
Drummond, J. et al.: “Characterization of Nonradioactive Assays for Cobalamin-Dependent and Cobalamin-Independent Methionine Synthase Enzymes”, Analytical Biochemistry, vol. 228, No. 2, 1995, pp. 323-329, XP002297999, ISSN: 0003-2697.
Huang, Longquan et al.: Assays of Methylenetetrahydrofolate Reductase and Methionine Synthase Activities by Monitoring 5-Methyltetrahydrofolate and Tetrahydorfolate Using High-Performance Liquid Chromatography with Fluorescence Detection, Analytical Biochemistry, vol. 299, No. 2, Dec. 15, 2001, pp. 253-259, XP002346121, ISSN: 0003-2697.
Solomon, Peter S. et al.: Methionine Synthase, A Gene Required for Methionine Synthesis, is Expressed in Planta byCladosporium fulvum, Molecular Plant Pathology, vol. 1, No. 5, Sep. 2000, pp. 315, 323, XP002346122, ISSN: 1464-6722.

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