Use of low molecular weight amino acids in ophthalmic compositio

Details Use of low molecular weight amino acids in ophthalmic compositio Use of low molecular weight amino acids in ophthalmic compositio

1995-12-18

1998-04-21

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514912, A61K 31195

Patent

active

057418179

ABSTRACT:
The use of glycine and other low molecular weight amino acids in ophthalmic compositions (e.g., preserved saline solutions) is described. These compounds have been found to enhance the efficacy of antimicrobial preservatives. The compounds also act as chelating agents, buffers and tonicity agents.

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Collin, et al., "The Effects of Na.sub.2 EDTA on Keratocytes and Endothelium of the Isolated Guinea Pig Cornea", International Contact Lens Clinic, vol. 9, No. 5, pp. 281-287 (Sep./Oct. 1982).

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