Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1989-04-28
1992-01-07
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
C09F 700
Patent
active
050792610
ABSTRACT:
Composition and methods are disclosed for antagonizing SRS-A, and especially LTD.sub.4, comprising the administration of LXA.sub.4 or an active derivative thereof to an animal. These compositions and methods are useful in the control of hemostasis, vascular reactivity, and especially vasoconstriction, and anaphylactic and allergic reactions in animals.
REFERENCES:
patent: 4560514 (1985-12-01), Samuelsson et al.
patent: 4576758 (1986-03-01), Morris
Scott, R. H. et al., Nature, 330:760-762 (1987).
Benowitz, N. L., Annu. Rev. Med., 41:277-288 (1990).
Samuelsson, B. et al., Science, 237:1171-1176 (1987).
Serhan, C. N. et al., Proc. Natl. Acad. Sci. USA, 81:5335-5339 (1984).
Dahlen, S. E. et al., Acta Physiol. Scand., 130:643-647 (1987).
Dahlen, S. E. et al., Adv. Exper. Med. Biol., 229:107-130 (Chapter 9), 1988.
Jacques, C. A. J. et al., Br. J. Pharmacol., 95:562-568 (1988).
Lefer, A. M. et al., Proc. Natl. Acad. Sci. USA, 85:8340-8344 (1988).
Badr, K. F. et al., J. Clin. Invest., 81:1702-1709 (1988).
Sheard, P. et al., in The Development of Anti-Asthma Drugs, D. R. Buckle, et al., eds., Butterworth, London, pp. 133-158 (1988).
Lefer, A. M. et al., ISI Atlas Sci. (Pharmacology), 2:109-115 (1988).
Cashman, J. R. et al., Drugs of Today, 24:723-732 (1988).
Badr, K. F. et al., Am. J. Physiol., 22:F239-F243 (1987).
Badr, K. F. et al., Biochm. Biophys. Res. Commun., 145:408-414 (1987).
Badr, K. F. et al., in Advances in Prostaglandin, Thromboxane and Leukotriene Research, vol. 19, B. Samuelsson et al., eds., Raven Press, New York (1989), pp. 233-236.
DeBoer, D. K. et al., Kidney Int. (Proc. 21st Annual Mtg. of the Am. Soc. Nephrology), Dec. 11-14, 1988.
Nicolaou et al., Chem. Abstracts, 1989, vol. 111:76329v.
Badr Kamal
Serhan Charles N.
Brigham and Women's Hospital
Lee Lester L.
Maebius Stephen B.
LandOfFree
Use of lipoxin A.sub.4 and its derivatives as antagonists for sl does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of lipoxin A.sub.4 and its derivatives as antagonists for sl, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of lipoxin A.sub.4 and its derivatives as antagonists for sl will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-822788