Use of leflunomide for inhibiting interleukin 1 beta

Details Use of leflunomide for inhibiting interleukin 1 beta Use of leflunomide for inhibiting interleukin 1 beta

1995-03-28

1996-09-17

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3142

Patent

active

055568700

ABSTRACT:
N-(4-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide is an effective compound for preventing and treating disorders in which interleukin 1 beta is involved. It is used as a pharmaceutical.

REFERENCES:
patent: 4351841 (1982-09-01), Kammerer et al.
patent: 4965276 (1990-10-01), Bartlett et al.
T. Zielinski et al., "Effects of Leflunomide (HWA 486) on Cell Cycle . . . ", Immunobiology, 186 (1-2):113 (1992).
T. Zielinski et al., "Effects of Leflunomide (HWA 486) on Expression . . . ", Agent Actions, 38 (1993).
T. Mattar et al., "Inhibition of the Epidermal Growth Factor Receptor . . . ", Fed. of European Biochemical Soc. 334(2):161-164 (1993).
T. T. Glant et al., "Immunomodulation of Proteoglycan-Induced Progressive Polyarthritis by Leflunomide", Immunopharmacology, 23:105-116 (1992).
R. R. Bartlett et al., "Leflunomide (HWA 486), a Novel Immunomodulating Compounds for the . . . ", Agents and Actions, 32 ( 1/2):10-21 (1991).
Chan, Rapid Communication, Inhibition of Tumor Necrosis Factor By Curcumin, A Phytochemcal, Biochemical Pharmacology, vol. 49, No. 11, pp. 1551-1556 (1995).

Affiliated with

Also associated with

Rating

Use of leflunomide for inhibiting interleukin 1 beta does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of leflunomide for inhibiting interleukin 1 beta, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of leflunomide for inhibiting interleukin 1 beta will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-413412