Use of laser speckle patterns for measurement of electrophoretic

Chemistry: physical processes – Physical processes – Crystallization

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23253R, 204180R, 204299R, 424 12, G01N 2726, G01N 3316

Patent

active

040110443

ABSTRACT:
Reduction in electrophoretic mobility of antigen-coated microscopic polystyrene spheres due to an antigen-antibody reaction is detected by observing changes in oscillation amplitude of speckle patterns (i.e., regions of light and dark) produced by laser light scattered by the particles as they are driven back and forth by a square wave electric field.

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patent: 3855094 (1974-12-01), Teppo
R. J. Cohen et al., Immunochemistry, 12(4), 349-351 (1975).

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