Use of lactide polymers for adhesion prophylaxis

Details Use of lactide polymers for adhesion prophylaxis Use of lactide polymers for adhesion prophylaxis

1997-01-02

1998-12-29

Truong, Duc

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From carboxylic acid or derivative thereof

528310, 528503, 424443, 424444, 525419, 525461, C08G 6308

Patent

active

058543813

ABSTRACT:
The invention relates to the use of absorbable physiologically acceptable sheets of copolymers for preventing postoperative adhesions after surgical procedures and is characterized in that the sheets consist of racemic lactide and .epsilon.-caprolactone, .sigma.-valerolactone, .tau.-decalactone or .beta.-hydroxybutyric acid, prepared by reacting the monomers in the molar ratio of lactide to partner in the reaction of from 90 to 70 30 to 10 with the addition of metal carboxylates which are known per se as initiator, with a ratio of partner in the reaction to initiator of from 300:1 to more than 1000:1 at temperatures of 130.degree.-150.degree. C. over a period of 24 to 96 hours.

REFERENCES:
patent: 5206341 (1993-04-01), Ibay et al.

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