Use of L-acetylcarnitine for the treatment of AIDS

Details Use of L-acetylcarnitine for the treatment of AIDS Use of L-acetylcarnitine for the treatment of AIDS

1994-12-27

1997-08-12

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514451, 514459, 514556, 514931, 514934, 514967, 514969, 424430, 424433, 424436, A61K 31535, A61K 3135

Patent

active

056566280

ABSTRACT:
This invention relates to the use of L-acylcarnitine for the preparation of a drug and a technique for relieving the disease symptoms appearing in AIDS by administering an L-acylcarnitine. The invention furthermore relates to a drug for this purpose, characterized in content by L-acylcarnitine as active principle. The preferred L-acylcarnitine is L-acetylcarnitine.

REFERENCES:
patent: 4415588 (1983-11-01), Cavazza
patent: 5314689 (1994-05-01), Scandurra et al.
De Simone, C., et al., Acetyl-L Carnitine as a Modulator of the Neuro-Endocrine--Immune Interaction in HIV + Subjects. Excerpta Medica, Amsterdam (1989) 128: 125-138.
De Simone, C, et al., Amelioration of the Depression of HIV--Infected Subjects with L-Acetyl Carnitine Therapy. J Drug Dev, (1988) 1(3): 163-166
De Simone, C., et al., High Dose L-Carnitine Improves Immunologic and Metabolic Parameters in AIDS Patients. Immunopharmacology and Immunotoxicology (1993) 15 (1): 1-12.

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