Use of KPV tripeptide for dermatological disorders

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S002600

Reexamination Certificate

active

11049063

ABSTRACT:
The present invention is directed to a prevention and treatment for dermatological disorders. One aspect of this invention involves a dermatological treatment comprising one or more polypeptides with an amino acid sequence including KPV (SEQ. ID. NO. 1), MEHFRWGKPV (SEQ. ID. NO. 2), HFRWGKPV (SEQ. ID. NO. 3), or SYSMEHFRWGKPV (SEQ. ID. NO. 4) for the treatment and prevention of dermatological disorders. The polypeptides are at a level to effectively treat the cutaneous inflammation and are carried by a carrier. The one or more polypeptides can also be a dimer formed from any of the amino acid sequence above.

REFERENCES:
Ichiyama et al. 2000, Ann. N.Y. Acad. Sci., vol. 917, pp. 221-226.
Saunders et al., 2001, J. Biol. Chem., vol. 276, No. 22, pp. 18897-18904.
The Merk Manual, 16th Edition, 1992, pp. 2407-2409.
Stedman, T.L. 2000. Stedman's Medical Dictionary. Lippincott Williams & Wilkins, Philadelphia. xxxvi, 2098 pp. 897-898.

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