Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1997-06-09
1999-10-12
Mertz, Prema
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
514 2, 514 8, 514 12, 514885, 530351, 435 6952, A61K 3820
Patent
active
059651229
ABSTRACT:
Mammalian Interleukin-7 proteins (IL-7s)g DNAs and expression vectors encoding mammalian IL-7s, end processes for producing mammalian IL-7s as products of cell culture, including recombinant systems, are disclosed.
REFERENCES:
patent: 4425437 (1984-01-01), Riggs
patent: 4518584 (1985-05-01), Mark et al.
patent: 4530901 (1985-07-01), Weissman
patent: 4703008 (1987-10-01), Lin
patent: 4720482 (1988-01-01), Cantor et al.
patent: 4730036 (1988-03-01), Ralph et al.
patent: 4902288 (1990-02-01), Ingram
patent: 4956281 (1990-09-01), Wallner et al.
patent: 4965195 (1990-10-01), Namen et al.
patent: 4968607 (1990-11-01), Dower et al.
patent: 5032396 (1991-07-01), Williams et al.
patent: 5032676 (1991-07-01), Deeley et al.
patent: 5037756 (1991-08-01), Bollum et al.
patent: 5071972 (1991-12-01), Larsen
patent: 5081019 (1992-01-01), Wallner et al.
patent: 5116738 (1992-05-01), Wang et al.
patent: 5128450 (1992-07-01), Urdal et al.
patent: 5134121 (1992-07-01), Mobley et al.
patent: 5141856 (1992-08-01), Collins et al.
patent: 5229115 (1993-07-01), Lynch
patent: 5705149 (1998-01-01), Namen et al.
Oliver and Ward, A Dictionary of Genetic Engineering, p. 49, Cambridge University Press, Cambridge (1985).
Paige, C.S., "Surface immunoglobulin-negative B-cell precursors detected by formation of antibody-secreting colonies in agar," Nature 302:711, 1983.
Paige et al., "Differentiation of murine B cell precursors in agar culture. Frequency, surface marker analysis and requirements for growth," Eur. J. Immunol. 14:979-987, 1984.
Giri et al., "Interleukin-1-mediated induction of K-light chain synthesis and surface immunoglobulin expression on pre-B cells," J. Immunol. 132:223, 1984.
Jyonouchi et al., "Humoral factors in very young NZB mice that enhance the maturation of normal B cell precursors. Partial purification and characterization," J. Immunol. 135:1981, 1985.
Landreth et al., "Regulation of human B lymphopoiesis: Effect of a urinary activity associated with cyclic neutropenia," J. Immunol. 134:2305, 1985.
Whitlock et al., "Murine B cell lymphopoiesis in long term culture," J. Immunol. Meth. 67:353, 1984.
Whitlock et al., "Bone marrow stromal cell lines with lymphopoietic activity express high levels of pre-B neoplasia-associated molecule," Cell 48:1009-1021, 1987.
Hunt et al., "A single bone marrow-derived stomal cell type supports the in vitro growth of early lymphoid and myeloid cells," Cell 48:997-1007, 1987.
Namen et al., "B cell precursor growth-promoting activity," J. Exp. Med. 167:988-1002, 1988.
Namen et al., "Stimulation of B-cell progenitors by cloned murine interleukin-7," Nature 333:571-573, 1988.
Fung et al., "Molecular cloning of cDNA for murine interleukin-3," Nature 307:233-237, 1984.
Cerretti et al, "Cloning, sequence, and expression of bovine interleukin 2," Proc. Natl. Acad. Sci. USA 83:3223-3227, 1986.
Maniatis et al., in Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 224-246 and 404-433, 1982.
Goodwin et al., "Human interleukin 7: Molecular cloning and growth factor activity on human and murine B-lineage cells", Proc. Natl. Acad. Sci. USA 86:302-306, 1989.
Saeland et al., "Interleukin-7 Induces the Proliferation of Normal Human B-Cell Precursors", Blood 78:2229-2238, 1991.
Cosman et al., "Interleukin-7: a lymphoid growth factor active on T and B cell progenitors", Lymphokine Receptor Interactions 179:229-236, 1989.
Gessner et al., "Interleukin-7 Enhances Antimicrobial Activity Against Leishmania major in Murine Macrophages", Infection and Immunity 61:4008-4012, 1993.
Benjamin et al., "B Cell IL-7: Human B Cell Lines Constitutively Secrete IL-7 and Express IL-7 Receptors", J. Immunol. 152:4749-4757, 1994.
Baldwin et al., "Recombinant Interleukin-7 Induces Functional Activation of Cultured Human Macrophages by Down Regulating Both TGF-.beta. Expression and TGF-.beta. Protein Production", Abstract No. 84, 35th Annual Meeting of the American Society of Hematology, 1993.
Moran et al., "Regulation of HIV production by blood mononuclear cell from HIV-infected donors: I. Lack of correlation between HIV-1 production and T cell activation", Biol. Abstr. 96(6):AB-691, Abstract No. 65065.
Grabstein et al., "Inhibition of Murine B and T Lymphopoiesis In Vivo by an Anti-Interleukin-7 Monoclonal Antibody", J. Exp. Med. 178:257-264, 1993.
Finkelman et al., "Anti-Cytokine Antibodies as Carrier Proteins", J. Immunol. 151:1235-1244, 1993.
Co-pending U.S. Application serial No. 08/152,950, filed Nov. 12, 1993, Grabstein et al., "Treatment of Microbial Infection by Monocyte Stimulation with Interleukin-7".
Matis et al., "Adoptive Immunotherapy of a Syngeneic Murine Leukemia with a Tumor-Specific Cytotoxic T Cell Clone and Recombinant Human Interleukin 2: Correlation with Clonal IL 2 Receptor Expression", J. Immunol. 136:3496-3501, 1986.
Harris et al., Tib Tech 11:42-46, 1993.
Lerner, Nature 299:592-596, 1982.
Cunningham et al Science, vol. 244, pp. 1081-1085, 1989.
George et al., Macromolecular Sequencing & Synthesis, Selected Methods & Applications pp. 127-149, Alan R. Liss, Inc. N.Y., 1988.
Goodwin Raymond G.
Lupton Stephen D.
Mochizuki Diane Y.
Namen Anthony E.
Alexander Michael D.
Bauman Mary P.
Mertz Prema
Sanofi
LandOfFree
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