Use of interleukin-7 to induce monocytes/macrophages cytotoxic a

Details Use of interleukin-7 to induce monocytes/macrophages cytotoxic a Use of interleukin-7 to induce monocytes/macrophages cytotoxic a

1995-05-15

1997-10-28

Ulm, John

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

514 2, 514 8, 514885, 530351, C07K 1454, A61K 3820

Patent

active

056815573

ABSTRACT:
There is disclosed a method of treating microbial infections in microbially infected mammals and a method of augmenting antitumor immunotoxicity in a mammal comprising administering a therapeutically effective amount of IL-7 in a pharmaceutically acceptable carrier. There is further disclosed a method of stimulating macrophages to produce cytokines made by activated macrophages and a method for improving T cell presentation by a macrophage comprising administering a therapeutically effective amount of IL-7. Further, antimicrobial activity of macrophages can be improved by administering a combination of IL-7 and Interferon-.gamma..

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