Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1992-02-28
1996-01-02
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
514801, 514882, 523113, 523121, 525 541, 530356, A61F 202, A61K 3839, C07K 1520
Patent
active
054806445
ABSTRACT:
This invention discloses methods of repairing structurally defective or inadequately functioning muscles of the anal sphincter and methods of improving the competency of incompetent anal sphincters by administering an effective amount of an injectable biomaterial into the defect or into the anal sinuses. Preferred biomaterials to be used in this invention are collagen formulations.
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U.S. Ser. No. 06/619,028, inventor: O'Connor, "Method Of Improving The Competency Of Defective Sphincters," Filed Jun. 11, 1984 and abandoned on Aug. 27, 1985.
K. W. O'Connor, MD, and G. A. Lehman, MD, (1988) "Endoscopic placement of collagen at the lower esophageal sphincter to inhibit gastroesophageal reflux: a pilot study of 10 medically intractable patients," Gastrointestinal Endoscopy, 34(2):106-112.
Linda M. Dairiki Shortliffe, Fuad S. Freiha, Robert Kessler, Thomas A. Stamey, and Christos E. Constantinou, (Mar. 1989) "Treatment of Urinary Incontinence By The Periurethral Implantation Of Glutaraldehyde Cross-Linked Collagen," The Journal of Urology, 141:538-541.
Azpuru Carlos A.
JSF Consultants Ltd.
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