Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-09-05
1998-11-24
Owens, Amelia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514365, 514372, 514473, 514461, 514484, A61K 3138, A61K 31425, A61K 3134, A61K 3127
Patent
active
058407464
ABSTRACT:
The present invention provides a method of treating a neurodegenerative disease and in particular Alzheimers disease which comprises administering to a human in need thereof a therapeutically effective amount of a non-steroid COX-II inhibitor. Although a wide range of COX-II inhibitors may be employed but it is preferred to employ compounds of the Formula I: ##STR1##
REFERENCES:
patent: 4375479 (1983-03-01), Schroeder et al.
patent: 5192753 (1993-03-01), McGeer et al.
patent: 5343991 (1994-09-01), Premiski et al.
patent: 5409944 (1995-04-01), Black et al.
patent: 5436265 (1995-07-01), Black et al.
patent: 5474995 (1995-12-01), Ducharme et al.
patent: 5571810 (1996-11-01), Matsuo et al.
patent: 5604260 (1997-02-01), Guay et al.
patent: 5643960 (1997-07-01), Breitner et al.
patent: 5670527 (1997-09-01), Adams et al.
D.E. Griffin, et al., Ann. Neurol., vol. 35, No. 5, May 1994 pp. 592-597.
McGeer, et al., Neurology, 42, pp. 447-449, (Feb. 1992).
McGeer, et al., Can. J. Neurol. Sci. 16:4 (suppl) pp. 516-527, (1989).
Meyer, et al., JAGS, 37, pp. 549-555, (1989).
McGeer, et al., Lancet, 335, p. 1037, (1990).
Oken, et al., Alzheimer Disease and Associated Disorders, 6, No. 1, pp. 53-55 (1992).
Medical World News, pp. 16-17, (Feb. 12, 1990).
M.L. Jenkinson, et al., Br. J. Rheumatol, 28(1) pp. 86-88, (1989) "Rheumatoid Arthritis and Senile Dementia of the Alzheimer's Type".
A.S. Henderson, et al., Psychological Medicine, 22, pp. 429-436, (1992), "Environmental Risk Factors for Alzheimer's Disease . . . ".
A.S. Henderson, et al., Acta Psychiatr. Scand., 78, pp. 257-275, (1988), "The Risk Factors for Alzheimer's Disease: A Review and a Hypothesis".
Ducharme Yves
Gauthier Jacques Yves
Leblanc Yves
Leger Serge
Prasit Petpiboon
Merck Frosst Canada Inc.
Owens Amelia
Panzer Curtis C.
Rose David L.
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