Use of indigestible oligosaccharides to prevent gastrointestinal

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical

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424439, 42419711, 4241951, 424 73, 514867, 514 54, A61K 968

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058275266

ABSTRACT:
A method is provided for reducing the duration of diarrhea and recurrent episodes of diarrhea in humans by enterally administering indigestible oligosaccharides prophylactically. More specifically, the present invention relates to a method using indigestible oligosaccharides or fructooligosaccharides (FOS) to reduce the duration and recurrence of diarrhea in a human wherein between 0.5 grams and 5 grams of at least one FOS selected from the group consisting of 1-kestose, nystose, and 1.sup.F -.beta.-fructofuranosyl nystose is administered to said human per day. The indigestible oligosaccharides can be produced through enzymatic synthesis, chemical techniques or isolated from plant materials and are administered in the form of a nutritional product, candy, tablets, chewing gum, lozenges, milk, yogurts, fermented products and the like.

REFERENCES:
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patent: 4987124 (1991-01-01), Speights et al.
patent: 5219842 (1993-06-01), Okada et al.
patent: 5437880 (1995-08-01), Takaichi et al.
patent: 5444054 (1995-08-01), Garleb et al.
Patent Abstracts of Japan, vol. 9, No. 287 (C-314), 14 Nov. 1985 and JP 60 133852 A (Zenkoku Shiyokubutsu Tanpaku Shiyokuhin Kiyoudoukumiai), 17 Jul. 1985; See abstract.
Faseb Journal, vol. 9, No. 3, 1995, p. A368 XP002025324, Chandra, G. et al.: "The addition of neosugar to oral electrolyte solutions (OES) for treatment of acute diarrhea", See Abstract.
Patent Abstracts of Japan, vol. 17, No. 670 (C-1139), 9 Dec. 1993 and JP 05 219897 A (Ajinomoto Co. Inc.), 31 Aug. 1993, See Abstract.
Database WPI, Week 8915, Derwent Publications Ltd., London, GB; AN 89-109964 XP002025325 & JP 01 055 150 A (Suntory Ltd.), 2 Mar. 1989, See Abstract.

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