Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2011-03-22
2011-03-22
Nickol, Gary B. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C536S023500
Reexamination Certificate
active
07910697
ABSTRACT:
The present invention relates to use of an antagonist of BIR1 (B cell immunoglobulin receptor 1) related to the present invention, a method for screening the antagonist, in addition to subtype polypeptides of BIR1, the polynucleotide encoding them and antibodies for the polypeptides.BIR1 functions as an immunosuppressive receptor, and the antagonist of BIR1 has immunopotentive activity, which is able to use for preventing and/or treating a cancer, an immunodeficiency disease or an infectious disease.
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patent: 7083793 (2006-08-01), Fraser
patent: 2004/0185045 (2004-09-01), Koenig et al.
patent: WO 99/33873 (1999-07-01), None
patent: 00/50443 (2000-08-01), None
Extended European Search Report dated Jun. 2, 2009.
Jay C Unkeless et al., “Inhibitory Receptors, ITIM Sequences and Phosphatases”, Current Opinion in Immunology, Jun. 1, 1997, pp. 338-343, vol. 9, No. 3.
Moroe Kimiho
Odani Tomoyuki
Tada Hideaki
Gamett Daniel C
Nickol Gary B.
Ono Pharmaceutical Co. Ltd.
Sughrue & Mion, PLLC
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