Use of imidazopyrazole derivatives as analgesics anti-inflammato

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5483031, 5142285, 5142328, 514255, 514269, 514307, 514314, 514322, 514338, 514365, 514372, 514374, 514378, 514383, A61K 31415, C07D23500

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056985762

ABSTRACT:
Described herein are compounds of formula (I): ##STR1## cycloalkyl, alkenyl, aralkyl, arylalkenyl, aryl, aromatic heterocyclic, cyano or halogen; R.sup.3 is hydrogen, optionally substituted alkyl, aralkyl or acyl; R.sup.4 and R.sup.5 are hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, aralkyl, arylalkenyl, aryl or aromatic heterocyclic!; and pharmaceutically acceptable salts thereof are analgesics and anti-inflammatory agents as well having anti-ulcer and 5-lipoxygenase inhibitory activities.

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Chemical Abstracts, vol. 82, No. 6 Abstracts 42, 451w, Feb. 10, 1973, p. 363.
Chemical Abstracts, vol. 82, No. 22, Abstract 156174p, Jun. 2, 1975, p. 597.
Kline, Ira, CA 81:45352, 1974.

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