Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Reexamination Certificate
2004-11-26
2011-12-06
Spector, Lorraine (Department: 1647)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
C435S375000, C435S384000, C435S386000, C530S351000
Reexamination Certificate
active
08071375
ABSTRACT:
The use of certain IL-6-type cytokines for the in vitro maturation of mammalian oocytes is described. The in vitro matured oocytes may be used in in vitro fertilization protocols.
REFERENCES:
patent: 4554101 (1985-11-01), Hopp
patent: 6274135 (2001-08-01), Keith et al.
patent: 2001/0028878 (2001-10-01), Lindenberg et al.
patent: WO 97/30146 (1997-08-01), None
E. Nilsson et al., “Leukemia inhibitory factor (LIF) induces the primordial to primary follicle transitionin rat ovaries”, Mol. Cel. Endocrinol. 188:65-75, Feb. 25, 2002.
P. R. Kezele et al., “Insulin but not insulin-like growth factor-1 promotes the primordial to primary follicle transition”, Mol. Cell. . Endocrinol. 192:37-43, 2002 (Feb. 28, 2003).
C. Huyser et al., “Interleukine-1beta, Interleukin-6, and Growth Hormone Levels in Human Follicular Fluid”, J. Assisted Reprod. and Genet., 11(4):193-202, 1994.
T. Taga; “gp130 and the Interleukin-6 Family of Cytokines”. Annual Review of Immunology vol. 15: 797-819 (Volume publication date Apr. 1997).
N. Garrido et al., Follicular hormonal environment and embryo quality in women with endometriosis, Human Reproduction Update 2000, vol. 6 No. 1 pp. 67-74.
http://www.pdrel.com/View/StedmanSearch/DocumentRetrive.aspx?documentld=9628, accessed Sep. 20, 2010, definition of “cumulus”.
http://www.pdrel.com/View/StedmanSearch/DocumentRetrive.aspx?documentld=02783, accessed Sep. 20, 2010, defnition of “Antrum”.
Endotext.com,(http://www.endotext.org/female/female1/femaleframe1.htm) , paragraph on oocyte-granulosa cell connections, accessed Sep. 20, 2010.
Abe, T., et al., “Macrophage Differentiation Inducing Factor from Human Monocytic Cells Is Equivalent to Murine Leukemia Inhibitory Factor,” The Journal of Biological Chemistry, vol. 264, No. 15, pp. 8941-8945 (1989).
Baumann, H., et al., “Hepatocyte-Stimulating Factor III Shares Structural and Functional Identity with Leukemia-Inhibitory Factor,” The Journal of Immunology, vol. 143, No. 4, pp. 1163-1167 (1989).
Eckert, J., “mRNA Expression of Leukaemia Inhibitory Factor (LIF) and its Receptor Subunits Glycoprotein 130 and LIF-Receptor-13 in Bovine Embryos Derived in vitro or in vivo,” Molecular Human Reproduction, vol. 4, No. 10, pp. 957-967 (1998).
International Search Report dated Apr. 22, 2005 for PCT/US2004/039757.
Kawasaki, F., et al., “The Clinical Role of Interleukin-6 and Interleukin-6 Soluble Receptor in Human Follicular Fluids,” Clin. Exp. Ed., vol. 3, pp. 27-31 (2003).
Koopman, P., et al., “A Factor Produced by Feeder Cells Which Inhibits Embryonal Carcinoma Cell Differentiation,” Experimental Cell Research, vol. 154, pp. 233-242 (1984).
Kyte, J., et al., “A Simple Method for Displaying the Hydropathic Character of a Protein,” Journal of Molecular Biology, vol. 157, pp. 105-132 (1982).
Moreau, J., et al., “Leukaemia Inhibitory Factor is Identical to the Myeloid Growth Factor Human Interleukin for DA cells,” Nature, vol. 336, pp. 690-692 (1988).
Mori, M., et al., “Purification of a Lipoprotein Lipase-Inhibiting Protein Produced by a Melanoma Cell Line Associated with Cancer Cachexia,” Biochemical and Biophysical Research Communications, vol. 160, No. 3, pp. 1085-1092 (1989).
Pennica, D., et al., “Biological Activities and Binding to the Leukemia Inhibitory Factor Receptor/gp130 Signaling Complex,” The Journal of Biological Chemistry, vol. 270, No. 18, pp. 10915-10922 (1995).
Picton, H., et al., “Growth and Maturation of Oocytes in vitro,” Reproduction Supplement, vol. 61, pp. 445-462 (2003).
Smith, A., et al., “Buffalo Rat Liver Cells Produce a Diffusible Activity Which Inhibits the Differentiation of Murine Embryonal Carcinoma and Embryonic Stem Cells,” Developmental Biology, vol. 121, pp. 1-9 (1987).
Sutton, M., “Effects of in-vivo and in-vitro Environments on the Metabolism of the Cumulus-Oocyte Complex and its Influence on Oocyte Developmental Capacity,” Human Reproduction Update, vol. 9, No. 1, pp. 35-48 (2003).
Tomida, M., et al., “Purification of a Factor Inducing Differentiation of Mouse Myeloid Leukemic M1 Cells from Conditioned Medium of Mouse Fibroblast L929 Cells,” The Journal of Biological Chemistry, vol. 259, No. 17, pp. 10978-10982 (1984).
Yamamori, T., et al., “The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor,” Science, vol. 246, pp. 1412-1416 (1989).
Zolti, M., et al., “Cytokine Involvement in Oocytes and Early Embryos,” Fertility and Sterility, vol. 56, No. 2, (1991).
Liu, Zhilin, et al., “Interleukin-6: an Autocrine Regulator of the Mouse Cumulus Cell-Oocyte Complex Expansion Process,” Endocrinology, vol. 150, No. 7, pp. 3360-3368 (Jul. 2009).
Diamond, M., et al., “Human Follicular Fluid Insulin Concentrations,” Journal of Clinical Endocrinology & Metabolism, vol. 61, No. 5, pp. 990-992 (1985).
Clark Ann M.
de Matos Daniel Gustavo
Jackson Jennifer A.
Palmer Stephen S.
Tran Cam Anh T.
Merck Serono SA
Morgan & Lewis & Bockius, LLP
Spector Lorraine
LandOfFree
Use of IL-6-type cytokines for maturation of oocytes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of IL-6-type cytokines for maturation of oocytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of IL-6-type cytokines for maturation of oocytes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4301086